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Fengqiang Wang

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Articles 27
Citations 271
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Recent Articles
1.
Osko J, Rivera S, Wang F, Niedringhaus T
Anal Chim Acta . 2024 Nov; 1332:343349. PMID: 39580163
Clearance of residual Host Cell Proteins (HCPs) is critical for the manufacturing processes of biotherapeutics. HCPs have the potential to impact product efficacy and quality, posing a risk to patient...
2.
Ma H, Yang Y, Xu Z, Liu X, Wang F, Qiao Y, et al.
Int J Biol Macromol . 2024 May; 270(Pt 1):132142. PMID: 38719005
The severe negative effects of impurities adhering to the external surface of wearable devices can significantly influence the signal transmission, performance, and lifespan of hydrogel sensors. Herein, we developed an...
3.
Li Z, Zhang H, Yang D, Hu Z, Wang F, Zhang Z
Molecules . 2023 May; 28(10). PMID: 37241985
A niobium-doped HZSM-5 (H[Nb]ZSM-5) was prepared by a hydrothermal synthesis method. The morphology, phase structure, composition, pore structure, and acid content of the catalyst were characterized using a series of...
4.
Li N, Li C, Zhang X, Wang F, Li L, Liang J, et al.
Am J Transl Res . 2023 May; 15(4):2843-2849. PMID: 37193183
Objective: To explore the clinical value of human fecal Syndecan-2 (SDC2) gene methylation in colorectal cancer screening. Methods: There were 30 patients with colorectal cancer receiving treatment in Zhangjiakou First...
5.
Wang F, Li X, Swanson M, Guetschow E, Winston M, Smith J, et al.
Biotechnol Bioeng . 2022 Apr; 119(8):2088-2104. PMID: 35437754
Host cell proteins (HCPs) are a significant class of process-related impurities commonly associated with the manufacturing of biopharmaceuticals. However, due to the increased use of crude enzymes as biocatalysts for...
6.
McIntosh J, Liu Z, Andresen B, Marzijarani N, Moore J, Marshall N, et al.
Nature . 2022 Mar; 603(7901):439-444. PMID: 35296845
The introduction of molecular complexity in an atom- and step-efficient manner remains an outstanding goal in modern synthetic chemistry. Artificial biosynthetic pathways are uniquely able to address this challenge by...
7.
Li X, Wang F, Li H, Richardson D, Roush D
Antib Ther . 2022 Feb; 5(1):42-54. PMID: 35155990
Nonionic surfactant polysorbates, including PS-80 and PS-20, are commonly used in the formulation of biotherapeutic products for both preventing surface adsorption and acting as stabilizer against protein aggregation. Trace levels...
8.
Smith J, Ralbovsky N, Lauro M, Hoyt E, Guetschow E, Wang F, et al.
J Pharm Biomed Anal . 2021 Oct; 207:114393. PMID: 34607166
Recent advances in biocatalysis and directed enzyme evolution has led to a variety of enzymatically-driven, elegant processes for active pharmaceutical ingredient (API) production. For biocatalytic processes, quantitation of any residual...
9.
Jones M, Palackal N, Wang F, Gaza-Bulseco G, Hurkmans K, Zhao Y, et al.
Biotechnol Bioeng . 2021 Apr; 118(8):2870-2885. PMID: 33930190
Host cell proteins (HCPs) are process-related impurities that may copurify with biopharmaceutical drug products. Within this class of impurities there are some that are more problematic. These problematic HCPs can...
10.
Li X, An Y, Liao J, Xiao L, Swanson M, Martinez-Fonts K, et al.
Biotechnol Prog . 2021 Jan; 37(3):e3128. PMID: 33476097
Host cell proteins (HCPs) are process-related impurities derived from host organisms, which need to be controlled to ensure adequate product quality and safety. In this study, product quality attributes were...