Felix Randow
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Explore the profile of Felix Randow including associated specialties, affiliations and a list of published articles.
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51
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10356
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Recent Articles
1.
Crespillo-Casado A, Pothukuchi P, Naydenova K, Yip M, Young J, Boulanger J, et al.
EMBO Rep
. 2024 Oct;
25(11):4979-5005.
PMID: 39375464
Innate immunity senses microbial ligands known as pathogen-associated molecular patterns (PAMPs). Except for nucleic acids, PAMPs are exceedingly taxa-specific, thus enabling pattern recognition receptors to detect cognate pathogens while ignoring...
2.
Pruneda J, Randow F
Mol Cell
. 2024 Sep;
84(18):3378-3380.
PMID: 39303679
In two recent studies in Nature, Hör et al. and Chambers et al. report that ubiquitin-like conjugation in bacteria antagonizes phage replication.
3.
Boyle K, Ellison C, Elliott P, Schuschnig M, Grimes K, Dionne M, et al.
EMBO J
. 2023 Jul;
42(17):e113012.
PMID: 37409490
Invasive bacteria enter the cytosol of host cells through initial uptake into bacteria-containing vacuoles (BCVs) and subsequent rupture of the BCV membrane, thereby exposing to the cytosol intraluminal, otherwise shielded...
4.
Valeva S, Degabriel M, Michal F, Gay G, Rohde J, Randow F, et al.
Pathog Dis
. 2023 Apr;
81.
PMID: 37012222
Guanylate-Binding Proteins are interferon-inducible GTPases that play a key role in cell autonomous responses against intracellular pathogens. Despite sharing high sequence similarity, subtle differences among GBPs translate into functional divergences...
5.
Otten E, Werner E, Crespillo-Casado A, Boyle K, Dharamdasani V, Pathe C, et al.
Nature
. 2021 May;
594(7861):111-116.
PMID: 34012115
Ubiquitylation is a widespread post-translational protein modification in eukaryotes and marks bacteria that invade the cytosol as cargo for antibacterial autophagy. The identity of the ubiquitylated substrate on bacteria is...
6.
Wu X, Wu Y, Zheng R, Tang F, Qin L, Lai D, et al.
EMBO Rep
. 2021 May;
22(7):e51678.
PMID: 33987949
Mycobacterial arabinogalactan (AG) is an essential cell wall component of mycobacteria and a frequent structural and bio-synthetical target for anti-tuberculosis (TB) drug development. Here, we report that mycobacterial AG is...
7.
Lulla V, Wandel M, Bandyra K, Ulferts R, Wu M, Dendooven T, et al.
J Virol
. 2021 May;
95(14):e0066321.
PMID: 33963053
RNA structural elements occur in numerous single-stranded positive-sense RNA viruses. The stem-loop 2 motif (s2m) is one such element with an unusually high degree of sequence conservation, being found in...
8.
Hahn M, Covarrubias-Pinto A, Herhaus L, Satpathy S, Klann K, Boyle K, et al.
Proc Natl Acad Sci U S A
. 2021 May;
118(19).
PMID: 33947818
is an intracellular pathogen of a substantial global health concern. In order to identify key players involved in infection, we performed a global host phosphoproteome analysis subsequent to bacterial infection....
9.
Klionsky D, Abdel-Aziz A, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, et al.
Autophagy
. 2021 Feb;
17(1):1-382.
PMID: 33634751
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our...
10.
Canton J, Blees H, Henry C, Buck M, Schulz O, Rogers N, et al.
Nat Immunol
. 2021 Feb;
22(3):391.
PMID: 33531713
No abstract available.