Felix K M Lorenz
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Explore the profile of Felix K M Lorenz including associated specialties, affiliations and a list of published articles.
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5
Citations
94
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Recent Articles
1.
Chen X, Leisegang M, Gavvovidis I, Pollack S, Lorenz F, Schumacher T, et al.
Front Immunol
. 2025 Jan;
15():1524629.
PMID: 39776913
Generation of high avidity T cell receptors (TCRs) reactive to tumor-associated antigens (TAA) is impaired by tolerance mechanisms, which is an obstacle to effective T cell therapies for cancer treatment....
2.
Edes I, Clauss J, Stahn R, Japp A, Lorenz F
Methods Mol Biol
. 2022 Jun;
2521:85-93.
PMID: 35732994
The efficient expression of T-cell receptors (TCRs) or chimeric antigen receptors (CARs) in primary human T cells is crucial for preclinical testing of receptor properties for adoptive T-cell therapies. Multiple...
3.
Liepe J, Sidney J, Lorenz F, Sette A, Mishto M
Cancer Immunol Res
. 2018 Nov;
7(1):62-76.
PMID: 30425108
Anticancer immunotherapies demand optimal epitope targets, which could include proteasome-generated spliced peptides if tumor cells were to present them. Here, we show that spliced peptides are widely presented by MHC...
4.
Bartsch Y, Rahmoller J, Mertes M, Eiglmeier S, Lorenz F, Stoehr A, et al.
Front Immunol
. 2018 Jun;
9:1183.
PMID: 29928274
Pro- and anti-inflammatory effector functions of IgG antibodies (Abs) depend on their subclass and Fc glycosylation pattern. Accumulation of non-galactosylated (agalactosylated; G0) IgG Abs in the serum of rheumatoid arthritis...
5.
Lorenz F, Ellinger C, Kieback E, Wilde S, Lietz M, Schendel D, et al.
Hum Gene Ther
. 2017 Sep;
28(12):1158-1168.
PMID: 28950731
T-cell receptor (TCR) immunotherapy uses T cells engineered with new TCRs to enable detection and killing of cancer cells. Efficacy of TCR immunotherapy depends on targeting antigenic peptides that are...
6.
Lorenz F, Wilde S, Voigt K, Kieback E, Mosetter B, Schendel D, et al.
PLoS One
. 2015 Mar;
10(3):e0121633.
PMID: 25799237
Codon optimization of nucleotide sequences is a widely used method to achieve high levels of transgene expression for basic and clinical research. Until now, immunological side effects have not been...