Felix Bormann
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Explore the profile of Felix Bormann including associated specialties, affiliations and a list of published articles.
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20
Citations
369
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Recent Articles
1.
Chteinberg E, Kolarova J, Vogt J, Macamo A, Bormann F, Kretzmer H, et al.
J Pathol
. 2025 Mar;
PMID: 40034069
Merkel cell carcinoma (MCC) is a highly malignant skin cancer that expresses epithelial-, neuroendocrine-, and lymphoid-associated genes. Here, we focused on B-cell differentiation, which is characterised by the coexpression of...
2.
Eckmann J, Fauti T, Biehl M, Zabaleta A, Blanco L, Lelios I, et al.
Blood
. 2024 Oct;
145(2):202-219.
PMID: 39476124
Despite several approved therapies, multiple myeloma (MM) remains an incurable disease with high unmet medical need. "Off-the-shelf" T-cell bispecific antibodies (TCBs) targeting B-cell maturation antigen (BCMA) and G protein-coupled receptor...
3.
Bogun L, Koch A, Scherer B, Germing U, Fenk R, Maus U, et al.
Cancers (Basel)
. 2024 Jun;
16(11).
PMID: 38893194
Myeloid and lymphoid neoplasms share the characteristics of potential bone marrow infiltration as a primary or secondary effect, which readily leads to hematopoietic insufficiency. The mechanisms by which clonal malignant...
4.
Bogun L, Koch A, Scherer B, Fenk R, Maus U, Bormann F, et al.
Blood Adv
. 2024 Jan;
8(10):2575-2588.
PMID: 38241490
The hallmark of multiple myeloma (MM) is a clonal plasma cell infiltration in the bone marrow accompanied by myelosuppression and osteolysis. Premalignant stages such as monoclonal gammopathy of undetermined significance...
5.
Waldbillig F, Bormann F, Neuberger M, Ellinger J, Erben P, Kriegmair M, et al.
Diagnostics (Basel)
. 2023 Mar;
13(5).
PMID: 36899967
To date, only a single transcriptome-wide m6A sequencing study of clear cell renal cell carcinoma (ccRCC) has been reported, with no validation so far. Herein, by TCGA analysis of the...
6.
Differentiation-related epigenomic changes define clinically distinct keratinocyte cancer subclasses
Sole-Boldo L, Raddatz G, Gutekunst J, Gilliam O, Bormann F, Liberio M, et al.
Mol Syst Biol
. 2022 Sep;
18(9):e11073.
PMID: 36121124
Keratinocyte cancers (KC) are the most prevalent malignancies in fair-skinned populations, posing a significant medical and economic burden to health systems. KC originate in the epidermis and mainly comprise basal...
7.
Simon T, Riemer P, Jarosch A, Detjen K, Di Domenico A, Bormann F, et al.
Genome Med
. 2022 Mar;
14(1):24.
PMID: 35227293
Background: Pancreatic neuroendocrine neoplasms (PanNENs) fall into two subclasses: the well-differentiated, low- to high-grade pancreatic neuroendocrine tumors (PanNETs), and the poorly-differentiated, high-grade pancreatic neuroendocrine carcinomas (PanNECs). While recent studies suggest...
8.
Jager P, Geyh S, Twarock S, Cadeddu R, Rabes P, Koch A, et al.
Stem Cells
. 2021 May;
39(9):1270-1284.
PMID: 34013984
Acute myeloid leukemia (AML) is characterized by an expansion of leukemic cells and a simultaneous reduction of normal hematopoietic precursors in the bone marrow (BM) resulting in hematopoietic insufficiency, but...
9.
Dengl S, Mayer K, Bormann F, Duerr H, Hoffmann E, Nussbaum B, et al.
Nat Commun
. 2020 Oct;
11(1):4974.
PMID: 33009381
Generation of bispecific antibodies (bsAbs) requires a combination of compatible binders in formats that support desired functionalities. Here, we report that bsAb-matrices can be generated by Format Chain Exchange (FORCE),...
10.
Chteinberg E, Vogt J, Kolarova J, Bormann F, van den Oord J, Speel E, et al.
Epigenetics
. 2020 Jun;
15(12):1319-1324.
PMID: 32475296
Merkel cell carcinoma (MCC) is a very rare, but highly aggressive skin cancer which occurs mainly in elderly patients. MCC cells show an expression pattern of three cell lineages: epithelial,...