Felicity C Jackling
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Explore the profile of Felicity C Jackling including associated specialties, affiliations and a list of published articles.
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8
Citations
230
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Recent Articles
1.
Dawson C, Milevskiy M, Capaldo B, Yip R, Song X, Vaillant F, et al.
Cell Rep
. 2024 Dec;
43(12):115073.
PMID: 39700014
Hormone-receptor-positive (HR) luminal cells largely mediate the response to estrogen and progesterone during mammary gland morphogenesis. However, there remains a lack of consensus on the precise nature of the precursor...
2.
Nightingale R, Reehorst C, Vukelic N, Papadopoulos N, Liao Y, Guleria S, et al.
Dev Cell
. 2024 May;
59(15):1988-2004.e11.
PMID: 38781975
The transcription factor EHF is highly expressed in the lactating mammary gland, but its role in mammary development and tumorigenesis is not fully understood. Utilizing a mouse model of Ehf...
3.
Joyce R, Pascual R, Heitink L, Capaldo B, Vaillant F, Christie M, et al.
Nat Cell Biol
. 2024 Jan;
26(1):138-152.
PMID: 38216737
Inheritance of a BRCA2 pathogenic variant conveys a substantial life-time risk of breast cancer. Identification of the cell(s)-of-origin of BRCA2-mutant breast cancer and targetable perturbations that contribute to transformation remains...
4.
Rios A, Capaldo B, Vaillant F, Pal B, van Ineveld R, Dawson C, et al.
Cancer Cell
. 2019 Jun;
35(6):953.
PMID: 31185217
No abstract available.
5.
Rios A, Capaldo B, Vaillant F, Pal B, van Ineveld R, Dawson C, et al.
Cancer Cell
. 2019 Apr;
35(4):618-632.e6.
PMID: 30930118
Breast tumors are inherently heterogeneous, but the evolving cellular organization through neoplastic progression is poorly understood. Here we report a rapid, large-scale single-cell resolution 3D imaging protocol based on a...
6.
Fu N, Pal B, Chen Y, Jackling F, Milevskiy M, Vaillant F, et al.
Dev Cell
. 2018 Dec;
47(5):629-644.e8.
PMID: 30523786
Long-lived quiescent mammary stem cells (MaSCs) are presumed to coordinate the dramatic expansion of ductal epithelium that occurs through the different phases of postnatal development, but little is known about...
7.
Pal B, Chen Y, Vaillant F, Jamieson P, Gordon L, Rios A, et al.
Nat Commun
. 2017 Nov;
8(1):1627.
PMID: 29158510
The mammary epithelium comprises two primary cellular lineages, but the degree of heterogeneity within these compartments and their lineage relationships during development remain an open question. Here we report single-cell...
8.
Jackling F, Johnson W, Appleton B
J Hered
. 2012 Nov;
105(6):847-57.
PMID: 23144493
White-spotting patterns in mammals can be caused by mutations in the gene KIT, whose protein is necessary for the normal migration and survival of melanocytes from the neural crest. The...