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Felicitas Lewrick

Explore the profile of Felicitas Lewrick including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 63
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Recent Articles
1.
Scherzinger-Laude K, Schonherr C, Lewrick F, Suss R, Francese G, Rossler J
Int J Nanomedicine . 2013 Jul; 8:2197-211. PMID: 23818777
Background: Patupilone (EPO906) is a microtubule stabilizer with a potent antitumor effect. Integrin αVβ3-binding (RGD) liposomes were loaded with EPO906, and their antitumor efficacy was evaluated in two pediatric tumor...
2.
Hantel C, Lewrick F, Reincke M, Suss R, Beuschlein F
J Endocrinol . 2012 Mar; 213(2):155-61. PMID: 22407999
Adrenocortical carcinoma (ACC) is a rare endocrine tumor entity with poor prognosis. Medical treatment is limited to common cytotoxic agents, which are associated with low treatment responses. Thus, lack of...
3.
Gubernator J, Chwastek G, Korycinska M, Stasiuk M, Grynkiewicz G, Lewrick F, et al.
J Control Release . 2010 Jun; 146(1):68-75. PMID: 20510316
The purpose of this study was to design a new stable liposomal formulation for the anticancer drug idarubicin. Idarubicin is a relatively hydrophobic member of the anthracycline family. It exhibits...
4.
Lewrick F, Suss R
Methods Mol Biol . 2010 Jan; 605:139-45. PMID: 20072878
The following chapter introduces a remote loading procedure for anthracyclines focussing on the well-established drug doxorubicin. The key advantage of remote loading is that it leads to higher drug to...
5.
Huber K, Schemies J, Uciechowska U, Wagner J, Rumpf T, Lewrick F, et al.
J Med Chem . 2009 Dec; 53(3):1383-6. PMID: 20030343
Class III histone deacetylases (sirtuins) play pivotal roles in many cellular processes. They are linked to extended lifespan and to the pathogenesis of cancer and neuronal disorders. We present novel...
6.
Hantel C, Lewrick F, Schneider S, Zwermann O, Perren A, Reincke M, et al.
J Clin Endocrinol Metab . 2009 Dec; 95(2):943-52. PMID: 19952224
Context: Through overexpression and aberrant activation in many human tumors, the IGF system plays a key role in tumor development and tumor cell proliferation. Different strategies targeting IGF-I receptor (IGFI-R)...
7.
Gantert M, Lewrick F, Adrian J, Rossler J, Steenpass T, Schubert R, et al.
Pharm Res . 2008 Nov; 26(3):529-38. PMID: 19015959
Purpose: The challenge in developing liposomes to be used in active drug targeting is to design a method that can be used for modifying liposomal membranes that is applicable for...