Felicia Ranta
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Explore the profile of Felicia Ranta including associated specialties, affiliations and a list of published articles.
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14
Citations
720
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Recent Articles
1.
Braumuller H, Wieder T, Brenner E, Assmann S, Hahn M, Alkhaled M, et al.
Nature
. 2013 Feb;
494(7437):361-5.
PMID: 23376950
Cancer control by adaptive immunity involves a number of defined death and clearance mechanisms. However, efficient inhibition of exponential cancer growth by T cells and interferon-γ (IFN-γ) requires additional undefined...
2.
Ranta F, Leveringhaus J, Theilig D, Schulz-Raffelt G, Hennige A, Hildebrand D, et al.
PLoS One
. 2012 Jan;
6(12):e28828.
PMID: 22216119
Background: High fat diet-induced hyperglycemia and palmitate-stimulated apoptosis was prevented by specific inhibition of protein kinase C delta (PKCδ) in β-cells. To understand the role of PKCδ in more detail...
3.
Klose C, Straub I, Riehle M, Ranta F, Krautwurst D, Ullrich S, et al.
Br J Pharmacol
. 2011 Jan;
162(8):1757-69.
PMID: 21198543
Background And Purpose: Fenamates are N-phenyl-substituted anthranilic acid derivatives clinically used as non-steroid anti-inflammatory drugs in pain treatment. Reports describing fenamates as tools to interfere with cellular volume regulation attracted...
4.
Heni M, Ketterer C, t Hart L, Ranta F, van Haeften T, Eekhoff E, et al.
J Clin Endocrinol Metab
. 2010 Sep;
95(12):E479-84.
PMID: 20826583
Context: Single-nucleotide polymorphisms (SNPs) within the G6PC2 locus are associated with fasting glucose and insulin secretion. These SNPs are not associated with type 2 diabetes risk. Objective: Our objective was...
5.
Hennige A, Ranta F, Heinzelmann I, Dufer M, Michael D, Braumuller H, et al.
Diabetes
. 2009 Oct;
59(1):119-27.
PMID: 19826167
Objective: In vitro models suggest that free fatty acid-induced apoptotic beta-cell death is mediated through protein kinase C (PKC)delta. To examine the role of PKCdelta signaling in vivo, transgenic mice...
6.
Weyrich P, Staiger H, Stancakova A, Schafer S, Kirchhoff K, Ullrich S, et al.
BMC Med Genet
. 2009 Aug;
10:77.
PMID: 19682370
Background: Neuron-derived orphan receptor (Nor) 1, nuclear receptor (Nur) 77, and nuclear receptor-related protein (Nurr) 1 constitute the NR4A family of orphan nuclear receptors which were recently found to modulate...
7.
Zhang Y, Ranta F, Tang C, Shumilina E, Mahmud H, Foller M, et al.
Apoptosis
. 2009 Jun;
14(7):878-89.
PMID: 19488858
Amyloid peptides interfere with survival of pancreatic beta-cells. In some cells apoptosis is paralleled by ceramide-dependent alterations of ion channel activity. The purpose of the present study was to elucidate...
8.
Ranta F, Dufer M, Stork B, Wesselborg S, Drews G, Haring H, et al.
Cell Signal
. 2008 Jul;
20(10):1780-6.
PMID: 18611438
Previously, we described that apoptotic cell death induced by the synthetic glucocorticoid dexamethasone (dex) is inhibited by calcineurin inhibitors, FK506 and deltamethrin, in insulin-secreting cells. The aim of the present...
9.
Avram D, Ranta F, Hennige A, Berchtold S, Hopp S, Haring H, et al.
Cell Physiol Biochem
. 2008 May;
21(5-6):455-62.
PMID: 18453753
Appropriate insulin secretion depends on beta-cell mass that is determined by the balance between cell proliferation and death. IGF-1 stimulates proliferation and protects against apoptosis. In contrast, glucocorticoids promote cell...
10.
Dufer M, Haspel D, Krippeit-Drews P, Kelm M, Ranta F, Nitschke R, et al.
Cell Physiol Biochem
. 2007 Jun;
20(1-4):65-74.
PMID: 17595516
K(ATP) channel activity influences beta cell Ca(2+) homeostasis by regulating Ca(2+) influx through L-type Ca(2+) channels. The present paper demonstrates that loss of K(ATP) channel activity due to pharmacologic or...