Federico Scala
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Explore the profile of Federico Scala including associated specialties, affiliations and a list of published articles.
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22
Citations
758
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Recent Articles
1.
Bernaerts Y, Deistler M, Goncalves P, Beck J, Stimberg M, Scala F, et al.
bioRxiv
. 2025 Jan;
PMID: 39803528
Neural cell types have classically been characterized by their anatomy and electrophysiology. More recently, single-cell transcriptomics has enabled an increasingly fine genetically defined taxonomy of cortical cell types, but the...
2.
Blanco F, Saifullah M, Cheng J, Abella C, Scala F, Firozi K, et al.
J Neurosci
. 2024 Dec;
45(6).
PMID: 39725519
Excitatory synapses and the actin-rich dendritic spines on which they reside are indispensable for information processing and storage in the brain. In the adult hippocampus, excitatory synapses must balance plasticity...
3.
Shen S, Jiang X, Scala F, Fu J, Fahey P, Kobak D, et al.
Nat Commun
. 2022 Oct;
13(1):6389.
PMID: 36302912
Neocortical feedback is critical for attention, prediction, and learning. To mechanically understand its function requires deciphering its cell-type wiring. Recent studies revealed that feedback between primary motor to primary somatosensory...
4.
Di Re J, Hsu W, Kayasandik C, Fularczyk N, James T, Nenov M, et al.
Front Mol Neurosci
. 2021 Jul;
14:643860.
PMID: 34276302
The axon initial segment (AIS) is a highly regulated subcellular domain required for neuronal firing. Changes in the AIS protein composition and distribution are a form of structural plasticity, which...
5.
Cheng J, Scala F, Blanco F, Niu S, Firozi K, Keehan L, et al.
J Neurosci
. 2020 Dec;
41(6):1191-1206.
PMID: 33328293
The dentate gyrus (DG) controls information flow into the hippocampus and is critical for learning, memory, pattern separation, and spatial coding, while DG dysfunction is associated with neuropsychiatric disorders. Despite...
6.
Scala F, Kobak D, Bernabucci M, Bernaerts Y, Cadwell C, Castro J, et al.
Nature
. 2020 Nov;
598(7879):144-150.
PMID: 33184512
Cortical neurons exhibit extreme diversity in gene expression as well as in morphological and electrophysiological properties. Most existing neural taxonomies are based on either transcriptomic or morpho-electric criteria, as it...
7.
Aceto G, Colussi C, Leone L, Fusco S, Rinaudo M, Scala F, et al.
Proc Natl Acad Sci U S A
. 2020 Mar;
117(14):8143-8153.
PMID: 32209671
Although major depressive disorder (MDD) is highly prevalent, its pathophysiology is poorly understood. Recent evidence suggests that glycogen-synthase kinase 3β (GSK3β) plays a key role in memory formation, yet its...
8.
Cadwell C, Scala F, Fahey P, Kobak D, Mulherkar S, Sinz F, et al.
Elife
. 2020 Mar;
9.
PMID: 32134385
Clones of excitatory neurons derived from a common progenitor have been proposed to serve as elementary information processing modules in the neocortex. To characterize the cell types and circuit diagram...
9.
Scala F, Kobak D, Shan S, Bernaerts Y, Laturnus S, Cadwell C, et al.
Nat Commun
. 2019 Nov;
10(1):5075.
PMID: 31685814
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
10.
Scala F, Kobak D, Shan S, Bernaerts Y, Laturnus S, Cadwell C, et al.
Nat Commun
. 2019 Sep;
10(1):4174.
PMID: 31519874
Layer 4 (L4) of mammalian neocortex plays a crucial role in cortical information processing, yet a complete census of its cell types and connectivity remains elusive. Using whole-cell recordings with...