Federico Canzian
Overview
Explore the profile of Federico Canzian including associated specialties, affiliations and a list of published articles.
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329
Citations
12562
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Recent Articles
11.
Giaccherini M, Giaccherini M, Rende M, Gentiluomo M, Gentiluomo M, Corradi C, et al.
Mutagenesis
. 2024 Apr;
PMID: 38606763
Pleiotropic variants (i.e., genetic polymorphisms influencing more than one phenotype) are often associated with cancer risk. A scan of pleiotropic variants was successfully conducted ten years ago in relation to...
12.
Gentiluomo M, Dixon-Suen S, Farinella R, Peduzzi G, Canzian F, Milne R, et al.
J Endocr Soc
. 2024 Mar;
8(4):bvae017.
PMID: 38425433
Pancreatic cancer is currently the seventh leading cause of cancer death worldwide. Understanding whether modifiable factors increase or decrease the risk of this disease is central to facilitating primary prevention....
13.
Yiangou K, Mavaddat N, Dennis J, Zanti M, Wang Q, Bolla M, et al.
medRxiv
. 2024 Feb;
PMID: 38410445
The 313-variant polygenic risk score (PRS) provides a promising tool for breast cancer risk prediction. However, evaluation of the PRS across different European populations which could influence risk estimation has...
14.
Unal P, Lu Y, Bueno-de-Mesquita B, van Eijck C, Talar-Wojnarowska R, Szentesi A, et al.
Hum Genomics
. 2024 Feb;
18(1):12.
PMID: 38308339
Genome-wide association studies (GWAS) are a powerful tool for detecting variants associated with complex traits and can help risk stratification and prevention strategies against pancreatic ductal adenocarcinoma (PDAC). However, the...
15.
Peduzzi G, Felici A, Pellungrini R, Giorgolo F, Farinella R, Gentiluomo M, et al.
Dig Liver Dis
. 2023 Nov;
56(6):1054-1063.
PMID: 37985251
Background: The current knowledge on pancreatic ductal adenocarcinoma (PDAC) risk factors is limited and no study has comprehensively tested the exposome in combination with the genetic variability in relation to...
16.
Felici A, Peduzzi G, Giorgolo F, Spinelli A, Calderisi M, Monreale A, et al.
Environ Res
. 2023 Nov;
241:117562.
PMID: 37944693
Background: There is a growing body of evidence on the effect of the local environment exposure on cancer susceptibility. Nonetheless, several of the associations remain controversial. Moreover, our understanding of...
17.
Macauda A, Briem K, Clay-Gilmour A, Cozen W, Forsti A, Giaccherini M, et al.
Leukemia
. 2023 Sep;
37(11):2326-2329.
PMID: 37723249
No abstract available.
18.
Giaccherini M, Gori L, Gentiluomo M, Farinella R, Cervena K, Skieceviciene J, et al.
Carcinogenesis
. 2023 Sep;
44(8-9):642-649.
PMID: 37670727
Coding sequence variants comprise a small fraction of the germline genetic variability of the human genome. However, they often cause deleterious change in protein function and are therefore associated with...
19.
Piccardi M, Gentiluomo M, Bertoncini S, Pezzilli R, Eross B, Bunduc S, et al.
Biol Res
. 2023 Aug;
56(1):46.
PMID: 37574541
Background: The genomes of present-day non-Africans are composed of 1-3% of Neandertal-derived DNA as a consequence of admixture events between Neandertals and anatomically modern humans about 50-60 thousand years ago....
20.
Middha P, Wang X, Behrens S, Bolla M, Wang Q, Dennis J, et al.
Breast Cancer Res
. 2023 Aug;
25(1):93.
PMID: 37559094
Background: Genome-wide studies of gene-environment interactions (G×E) may identify variants associated with disease risk in conjunction with lifestyle/environmental exposures. We conducted a genome-wide G×E analysis of ~ 7.6 million common...