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Fathelrahman Mohammed

Explore the profile of Fathelrahman Mohammed including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 99
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Recent Articles
1.
Mukerabigwi J, Tang R, Cao Y, Mohammed F, Zhou Q, Zhou M, et al.
Bioconjug Chem . 2023 Jan; 34(2):377-391. PMID: 36716444
The multi-drug resistance (MDR) of cancers is one of the main barriers for the success of diverse chemotherapeutic methods and is responsible for most cancer deaths. Developing efficient approaches to...
2.
Ibrahim A, Twizeyimana E, Lu N, Ke W, Mukerabigwi J, Mohammed F, et al.
ACS Appl Bio Mater . 2022 Jan; 2(11):5099-5109. PMID: 35021452
High-efficiency endosomal escape of drug delivery nanocarriers for glutathione-based reduction-responsive drug release in cytoplasm can significantly enhance the therapeutic efficacy of the loaded therapeutic drugs. In this report, we develop...
3.
Almahi W, Yu K, Mohammed F, Kong P, Han W
Exp Cell Res . 2021 Nov; 410(1):112946. PMID: 34826424
The principle underlying radiotherapy is to kill cancer cells while minimizing the harmful effects on non-cancer cells, which has still remained as a major challenge. In relation, ferroptosis has recently...
4.
Japir A, Ke W, Li J, Mukerabigwi J, Ibrahim A, Wang Y, et al.
J Control Release . 2021 Oct; 339:418-429. PMID: 34662586
Combination chemo-immunotherapy of cancers has attracted great attention due to its significant synergistic antitumor effect. The response rates and therapeutic efficacy of immunotherapy can be enhanced significantly after proper combination...
5.
Zhou Q, Mohammed F, Wang Y, Wang J, Lu N, Li J, et al.
J Control Release . 2021 Sep; 339:130-142. PMID: 34560158
The inherent hypoxic microenvironment of solid tumors has an important influence on tumor growth, distant metastasis, and invasiveness. The heterogeneous distribution of hypoxic regions inside tumors limits the therapeutic efficacy...
6.
Mukerabigwi J, Han Y, Lu N, Ke W, Wang Y, Zhou Q, et al.
J Mater Chem B . 2021 Apr; 9(13):3055-3067. PMID: 33885667
Drug resistance of cisplatin significantly limits its therapeutic efficacy in clinical applications against different cancers. Herein, we develop a novel strategy to overcome cisplatin drug resistance through sensitizing cisplatin-resistant human...
7.
Yin W, Ke W, Lu N, Wang Y, Japir A, Mohammed F, et al.
Biomacromolecules . 2020 Jan; 21(2):921-929. PMID: 31961134
A remarkable hallmark of cancer cells is the heterogeneous coexistence of overproduced intracellular glutathione (GSH) and a high level of reactive oxygen species (ROS) compared with those in normal cells,...
8.
Mohammed F, Ke W, Mukerabigwi J, Japir A, Ibrahim A, Wang Y, et al.
ACS Appl Mater Interfaces . 2019 Aug; 11(35):31681-31692. PMID: 31397163
In situ modulation of the surface properties on the micellar drug delivery nanocarriers offers an efficient method to improve the drug delivery efficiency into cells while maintaining stealth and stability...
9.
Ke W, Li J, Mohammed F, Wang Y, Tou K, Liu X, et al.
ACS Nano . 2019 Jan; 13(2):2357-2369. PMID: 30699292
Therapeutic nanoreactors are of increasing interest in precise cancer therapy, which have been explored to in situ produce therapeutic compounds from inert prodrugs or intrinsic molecules at the target sites....