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Fatah Ouaaz

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Articles 9
Citations 286
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Recent Articles
1.
El-Barbry H, Capitao M, Barrin S, Amziani S, Pierre Paul P, Borreill S, et al.
J Immunol . 2020 Jun; 205(3):608-618. PMID: 32580933
Dendritic cells (DCs) are professional APCs, which sample Ags in the periphery and migrate to the lymph node where they activate T cells. DCs can also present native Ag to...
2.
Toubiana J, Courtine E, Tores F, Asfar P, Daubin C, Rousseau C, et al.
Ann Intensive Care . 2016 Apr; 6(1):28. PMID: 27059500
Background: cRel, a subunit of NF-κB, is implicated in the inflammatory response observed in autoimmune disease. Hence, knocked-out mice for cRel had a significantly higher mortality, providing new and important...
3.
Grimaldi D, Le Bourhis L, Sauneuf B, Dechartres A, Rousseau C, Ouaaz F, et al.
Intensive Care Med . 2013 Dec; 40(2):192-201. PMID: 24322275
Purpose: In between innate and adaptive immunity, the recently identified innate-like mucosal-associated invariant T (MAIT) lymphocytes display specific reactivity to non-streptococcal bacteria. Whether they are involved in bacterial sepsis has...
4.
Courtine E, Cagnard N, Mazzolini J, Antona M, Pene F, Fitting C, et al.
Innate Immun . 2012 Mar; 18(5):753-63. PMID: 22408080
NF-κB, which comprises homo- and hetero-dimers of the five members of the Rel family, plays a crucial role in immunity to infection. The cRel and p50 subunits have been implicated...
5.
Courtine E, Pene F, Cagnard N, Toubiana J, Fitting C, Brocheton J, et al.
Infect Immun . 2011 Feb; 79(5):1848-54. PMID: 21343350
NF-κB is a critical regulator of gene expression during severe infections. NF-κB comprises homo- and heterodimers of proteins from the Rel family. Among them, p50 and p65 have been clearly...
6.
Toubiana J, Courtine E, Pene F, Viallon V, Asfar P, Daubin C, et al.
Crit Care Med . 2010 Oct; 38(12):2287-94. PMID: 20890200
Objectives: Excessive inflammation is closely related to severity and outcome of sepsis. Because interleukin-1-receptor-associated kinase 1 is a key signaling protein in the activation of NF-κB during infection, we aimed...
7.
Pene F, Courtine E, Ouaaz F, Zuber B, Sauneuf B, Sirgo G, et al.
Infect Immun . 2009 Oct; 77(12):5651-8. PMID: 19805530
Depletion of dendritic cells (DC) in secondary lymphoid organs is a hallmark of sepsis-induced immune dysfunction. In this setting, we investigated if Toll-like receptor (TLR)-dependent signaling might modulate the maturation...
8.
Pene F, Zuber B, Courtine E, Rousseau C, Ouaaz F, Toubiana J, et al.
J Immunol . 2008 Dec; 181(12):8513-20. PMID: 19050269
Host infection by pathogens triggers an innate immune response leading to a systemic inflammatory response, often followed by an immune dysfunction which can favor the emergence of secondary infections. Dendritic...
9.
Wang J, Wang X, Hussain S, Zheng Y, Sanjabi S, Ouaaz F, et al.
J Immunol . 2007 May; 178(11):6777-88. PMID: 17513725
TLRs play a critical role in inducing inflammatory and immune responses against microbial agents. In this study, we have investigated the role of NF-kappaB transcription factors in regulating TLR-induced gene...