Faria Zafar
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Explore the profile of Faria Zafar including associated specialties, affiliations and a list of published articles.
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20
Citations
257
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Recent Articles
1.
Sastre D, Zafar F, Torres C, Piper D, Kirik D, Sanders L, et al.
Sci Rep
. 2023 Oct;
13(1):17796.
PMID: 37853101
Parkinson's disease (PD) is one of the most common neurodegenerative diseases, but no disease modifying therapies have been successful in clinical translation presenting a major unmet medical need. A promising...
2.
Chen M, Heinrich L, Zafar F, Sedov K, Schule B
Bio Protoc
. 2023 Jun;
13(11):e4689.
PMID: 37323631
Cell populations and tissues exhibit unique gene expression profiles, which allow for characterizing and distinguishing cellular subtypes. Monitoring gene expression of cell type-specific markers can indicate cell status such as...
3.
Ramos-Acevedo R, Morato-Torres C, Padilla-Godinez F, Bernal-Conde L, Palomero-Rivero M, Zafar F, et al.
Brain Sci
. 2023 Feb;
13(2).
PMID: 36831872
Transplantation of immature dopaminergic neurons or neural precursors derived from embryonic stem cells (ESCs) into the substantia nigra pars compacta (SNpc) is a potential therapeutic approach for functional restitution of...
4.
Sastre D, Zafar F, Torres C, Piper D, Kirik D, Sanders L, et al.
bioRxiv
. 2023 Feb;
PMID: 36747875
Parkinson's disease (PD) is one of the most common neurodegenerative diseases, but no disease modifying therapies have been successful in clinical translation presenting a major unmet medical need. A promising...
5.
Cheng C, Cleak J, Weiss L, Cater H, Stewart M, Wells S, et al.
Orphanet J Rare Dis
. 2022 Oct;
17(1):386.
PMID: 36280881
Background: Variants in the mitochondrial complex I assembly factor, NUBPL are associated with a rare cause of complex I deficiency mitochondrial disease. Patients affected by complex I deficiency harboring homozygous...
6.
Torres C, Zafar F, Tsai Y, Vazquez J, Gallagher M, McLaughlin I, et al.
HGG Adv
. 2022 Sep;
3(4):100137.
PMID: 36092952
Spinocerebellar ataxia type 10 (SCA10) is an autosomal-dominant disorder caused by an expanded pentanucleotide repeat in the gene. This repeat expansion, when fully penetrant, has a size of 850-4,500 repeats....
7.
Srinivasaraghavan V, Zafar F, Schule B
Bio Protoc
. 2022 Aug;
12(14).
PMID: 35978575
To optimize differentiation protocols for stem cell-based modeling applications, it is essential to assess the change in gene expression during the differentiation process. This allows controlling its differentiation efficiency into...
8.
Heinrich L, Zafar F, Torres C, Singh J, Khan A, Chen M, et al.
J Neurosci Methods
. 2022 Jun;
378:109653.
PMID: 35724898
Background: Human induced pluripotent stem cell (iPSC) models have been hailed as a breakthrough for understanding disease and developing new therapeutics. The major advantage of iPSC-derived neurons is that they...
9.
Zafar F, Srinivasaraghavan V, Chen M, Torres C, Schule B
Stem Cell Res
. 2022 Mar;
60:102733.
PMID: 35263701
Alpha-synuclein overexpression and aggregation are critical factors in the pathogenesis of Parkinson's disease (PD). Clinical cases with alpha-synuclein (SNCA) multiplications or deletions indicate that gene expression levels are essential for...
10.
Napolioni V, Fredericks C, Kim Y, Channappa D, Khan R, Kim L, et al.
Biomedicines
. 2022 Jan;
10(1).
PMID: 35052839
We describe the clinical and neuropathologic features of patients with Lewy body spectrum disorder (LBSD) carrying a nonsense variant, c.604C>T; p.R202X, in the glucocerebrosidase 1 () gene. While this variant...