Danuta Sastre
Overview
Explore the profile of Danuta Sastre including associated specialties, affiliations and a list of published articles.
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Articles
10
Citations
80
Followers
0
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Recent Articles
1.
Petraccione K, Ali M, Cyr N, Wahba H, Stocker T, Akhrymuk M, et al.
PLoS Pathog
. 2024 Mar;
20(3):e1012093.
PMID: 38512999
Rift Valley fever virus (RVFV) is a viral zoonosis that causes severe disease in ruminants and humans. The nonstructural small (NSs) protein is the primary virulence factor of RVFV that...
2.
Sastre D, Zafar F, Torres C, Piper D, Kirik D, Sanders L, et al.
Sci Rep
. 2023 Oct;
13(1):17796.
PMID: 37853101
Parkinson's disease (PD) is one of the most common neurodegenerative diseases, but no disease modifying therapies have been successful in clinical translation presenting a major unmet medical need. A promising...
3.
Sastre D, Zafar F, Torres C, Piper D, Kirik D, Sanders L, et al.
bioRxiv
. 2023 Feb;
PMID: 36747875
Parkinson's disease (PD) is one of the most common neurodegenerative diseases, but no disease modifying therapies have been successful in clinical translation presenting a major unmet medical need. A promising...
4.
Torres C, Wassouf Z, Zafar F, Sastre D, Outeiro T, Schule B
Int J Mol Sci
. 2020 Aug;
21(16).
PMID: 32785033
Neurodevelopmental and late-onset neurodegenerative disorders present as separate entities that are clinically and neuropathologically quite distinct. However, recent evidence has highlighted surprising commonalities and converging features at the clinical, genomic,...
5.
Sastre D, Baiochi J, Lima I, de Souza F, Corveloni A, Hassib Thome C, et al.
BMC Cancer
. 2019 Dec;
19(1):1239.
PMID: 31864341
Background: Colorectal cancer (CRC) is still a leading cause of death worldwide. Recent studies have pointed to an important role of microRNAs in carcinogenesis. Several microRNAs are described as aberrantly...
6.
Lima I, Lilian Dos Santos Schiavinato J, Paulino Leite S, Sastre D, Bezerra H, Sangiorgi B, et al.
Stem Cell Res Ther
. 2019 Jul;
10(1):202.
PMID: 31287022
Background: By post-transcriptionally regulating multiple target transcripts, microRNAs (miRNAs or miR) play important biological functions. H1 embryonic stem cells (hESCs) and NTera-2 embryonal carcinoma cells (ECCs) are two of the...
7.
Piper D, Sastre D, Schule B
Front Neurosci
. 2018 Apr;
12:199.
PMID: 29686602
Alpha-synuclein () plays a central role in the pathogenesis of Parkinson's disease (PD) and related Lewy body disorders such as Parkinson's disease dementia, Lewy body dementia, and multiple system atrophy....
8.
Zhang Y, Sastre D, Wang F
Curr Stem Cell Res Ther
. 2018 Feb;
13(4):243-251.
PMID: 29446747
Background: Induced pluripotent stem cells hold tremendous potential for biological and therapeutic applications. The development of efficient technologies for targeted genome alteration of stem cells in disease models is a...
9.
Sastre D, da Costa N, de Sa A, Conceicao S, Chiaratti M, Adona P, et al.
Theriogenology
. 2013 Nov;
81(2):326-31.
PMID: 24210669
In vitro-produced embryos store high lipid content in cytoplasmic lipid droplets (LD), and reduction or removal of LD has been demonstrated to improve freeze-thaw viability. The Perilipin Adipophilin Tail-interacting Protein...
10.
de Vasconcelos J, Moia L, Amaral I, Miranda E, Cicalisetakeshita L, de Oliveira L, et al.
Genet Mol Biol
. 2013 Apr;
36(1):22-7.
PMID: 23569404
Soroprevalence for Hepatitis C virus is reported as 2.12% in Northern Brazil, with about 50% of the patients exhibiting a sustained virological response (SVR). Aiming to associate polymorphisms in Killer...