Fari Ryan
Overview
Explore the profile of Fari Ryan including associated specialties, affiliations and a list of published articles.
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15
Citations
157
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Recent Articles
1.
Ryan F, Blex C, Ngo T, Kopp M, Michalke B, Venkataramani V, et al.
Acta Neuropathol
. 2024 Jun;
147(1):106.
PMID: 38907771
We show that redox active iron can induce a regulated form of non-apoptotic cell death and tissue damage called ferroptosis that can contribute to secondary damage and functional loss in...
2.
Ryan F, Francos-Quijorna I, Hernandez-Mir G, Aquino C, Schlapbach R, Bradbury E, et al.
J Neurosci
. 2024 Feb;
44(6).
PMID: 38326029
Toll-like receptors (TLRs) play an important role in the innate immune response after CNS injury. Although TLR4 is one of the best characterized, its role in chronic stages after spinal...
3.
Jhelum P, Zandee S, Ryan F, Zarruk J, Michalke B, Venkataramani V, et al.
Acta Neuropathol Commun
. 2023 Jul;
11(1):121.
PMID: 37491291
Ferroptosis is a form of lipid peroxidation-mediated cell death and damage triggered by excess iron and insufficiency in the glutathione antioxidant pathway. Oxidative stress is thought to play a crucial...
4.
Oprisoreanu A, Ryan F, Richmond C, Dzekhtsiarova Y, Carragher N, Becker T, et al.
Theranostics
. 2023 May;
13(8):2531-2551.
PMID: 37215570
Prolonged inflammation after spinal cord injury is detrimental to recovery. To find pharmacological modulators of the inflammation response, we designed a rapid drug screening paradigm in larval zebrafish followed by...
5.
David S, Ryan F, Jhelum P, Kroner A
Neuroscientist
. 2022 Jun;
29(5):591-615.
PMID: 35678019
Iron accumulation in the CNS occurs in many neurological disorders. It can contribute to neuropathology as iron is a redox-active metal that can generate free radicals. The reasons for the...
6.
Ramezani M, Ryan F, Sahraian M, Simani L
Mult Scler Relat Disord
. 2022 Feb;
57:103336.
PMID: 35158464
Background: Sexual dysfunction is common but underestimated clinical symptom in MS patients. A growing body of evidence has been suggested the link between brain lesions and sexual dysfunction (SD) in...
7.
Kieran N, Suresh R, Dorion M, Macdonald A, Blain M, Wen D, et al.
J Neuroinflammation
. 2022 Jan;
19(1):10.
PMID: 34991629
Background: Astrocytes are the most numerous glial cell type with important roles in maintaining homeostasis and responding to diseases in the brain. Astrocyte function is subject to modulation by microRNAs...
8.
David S, Jhelum P, Ryan F, Jeong S, Kroner A
Antioxid Redox Signal
. 2021 Sep;
37(1-3):150-170.
PMID: 34569265
Iron accumulation occurs in the central nervous system (CNS) in a variety of neurological conditions as diverse as spinal cord injury, stroke, multiple sclerosis, Parkinson's disease, and others. Iron is...
9.
Ryan F, Khoshnam S, Khodagholi F, Ashabi G, Ahmadiani A
Metab Brain Dis
. 2021 Jun;
36(7):1445-1467.
PMID: 34173922
Ischemic stroke is the second leading cause of mortality and disability globally. Neuronal damage following ischemic stroke is rapid and irreversible, and eventually results in neuronal death. In addition to...
10.
Simani L, Rezaei O, Ryan F, Sadeghi M, Hooshmandi E, Ramezani M, et al.
Basic Clin Neurosci
. 2021 Apr;
11(6):765-771.
PMID: 33850613
Introduction: Oxidative stress has recently emerged as a possible mechanism in the pathogenesis of epilepsy. Coenzyme Q10 (CoQ10) is a strong endogenous antioxidant that protects cells from lipid oxidation and...