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Fanny Aprahamian

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Articles 37
Citations 1114
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Recent Articles
1.
Abdellatif M, Vasques-Novoa F, Trummer-Herbst V, Durand S, Koser F, Islam M, et al.
Eur Heart J . 2025 Feb; PMID: 39995248
No abstract available.
2.
Pan H, Tian A, Chen H, Xia Y, Sauvat A, Moriceau S, et al.
Nat Metab . 2024 Nov; 6(12):2281-2299. PMID: 39578649
Cushing's syndrome is caused by an elevation of endogenous or pharmacologically administered glucocorticoids. Acyl coenzyme A binding protein (ACBP, encoded by the gene diazepam binding inhibitor, Dbi) stimulates food intake...
3.
Motino O, Lambertucci F, Joseph A, Durand S, Anagnostopoulos G, Li S, et al.
Cell Death Differ . 2024 Nov; 32(3):434-446. PMID: 39550516
Acyl-CoA binding protein (ACBP), also known as diazepam-binding inhibitor (DBI), is an extracellular checkpoint of autophagy. Here, we report that patients with histologically confirmed metabolic-associated steatohepatitis (MASH) or liver fibrosis...
4.
Chen H, Moriceau S, Joseph A, Mailliet F, Li S, Tolle V, et al.
Sci Transl Med . 2024 Aug; 16(760):eadl0715. PMID: 39141698
Extracellular acyl-coenzyme A binding protein [ACBP encoded by diazepam binding inhibitor (DBI)] is a phylogenetically ancient appetite stimulator that is secreted in a nonconventional, autophagy-dependent fashion. Here, we show that...
5.
Hofer S, Daskalaki I, Bergmann M, Friscic J, Zimmermann A, Mueller M, et al.
Nat Cell Biol . 2024 Aug; 26(9):1571-1584. PMID: 39117797
Caloric restriction and intermittent fasting prolong the lifespan and healthspan of model organisms and improve human health. The natural polyamine spermidine has been similarly linked to autophagy enhancement, geroprotection and...
6.
Alves Costa Silva C, Piccinno G, Suissa D, Bourgin M, Schreibelt G, Durand S, et al.
Nat Commun . 2024 Feb; 15(1):1633. PMID: 38395948
Tumor immunosurveillance plays a major role in melanoma, prompting the development of immunotherapy strategies. The gut microbiota composition, influencing peripheral and tumoral immune tonus, earned its credentials among predictors of...
7.
Cerrato G, Alvarez-Lucena C, Sauvat A, Hu Y, Forveille S, Chen G, et al.
Cell Death Dis . 2023 Nov; 14(11):758. PMID: 37989732
Autophagy inducers can prevent cardiovascular aging and age-associated diseases including atherosclerosis. Therefore, we hypothesized that autophagy-inducing compounds that act on atherosclerosis-relevant cells might have a protective role in the development...
8.
Zane F, Bouzid H, Sosa Marmol S, Brazane M, Besse S, Molina J, et al.
Aging Cell . 2023 Oct; 22(11):e13946. PMID: 37822253
Ageing is characterised at the molecular level by six transcriptional 'hallmarks of ageing', that are commonly described as progressively affected as time passes. By contrast, the 'Smurf' assay separates high-and-constant-mortality...
9.
Youssef L, Durand S, Aprahamian F, Lefevre D, Bourgin M, Maiuri M, et al.
Eur J Sport Sci . 2023 May; 23(11):2157-2169. PMID: 37161876
Physical activity and nutrition play important roles in preventing adverse health outcomes that accompany aging. It has been shown that high-intensity interval training (HIIT) combined with citrulline (CIT) supplementation can...
10.
Youssef L, Bourgin M, Durand S, Aprahamian F, Lefevre D, Maiuri M, et al.
Metabolites . 2023 Feb; 13(2). PMID: 36837817
Physical activity can be effective in preventing some of the adverse effects of aging on health. High-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) are beneficial interventions for the...