Faisal Thayyullathil
Overview
Explore the profile of Faisal Thayyullathil including associated specialties, affiliations and a list of published articles.
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28
Citations
929
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Recent Articles
1.
Subburayan K, Thayyullathil F, Pallichankandy S, Cheratta A, Alakkal A, Sultana M, et al.
Commun Biol
. 2024 Jun;
7(1):732.
PMID: 38886572
Ferroptosis is a unique iron-dependent form of non-apoptotic cell death characterized by devastating lipid peroxidation. Whilst growing evidence suggests that ferroptosis is a type of autophagy-dependent cell death, the underlying...
2.
Pallichankandy S, Thayyullathil F, Cheratta A, Subburayan K, Alakkal A, Sultana M, et al.
Cell Death Discov
. 2023 Mar;
9(1):94.
PMID: 36914635
Oxeiptosis is a recently identified reactive oxygen species (ROS)-sensitive, caspase independent, non-inflammatory regulated cell death pathway. The activation of Kelch-like ECH-associated protein 1-Phosphoglycerate mutase 5-Apoptosis inducing factor mitochondria associated 1...
3.
Alakkal A, Thayyullathil F, Pallichankandy S, Subburayan K, Cheratta A, Galadari S
Biomedicines
. 2022 Jul;
10(8).
PMID: 35892694
Sanguinarine (SNG) is a benzophenanthridine alkaloid isolated mainly from , , and . SNG is considered an antineoplastic agent based on its cytotoxic activity against various tumors. However, the exact...
4.
Cheratta A, Thayyullathil F, Hawley S, Ross F, Atrih A, Lamont D, et al.
Cell Rep
. 2022 May;
39(5):110761.
PMID: 35508122
AMP-activated protein kinase (AMPK) coordinates energy homeostasis during metabolic and energy stress. We report that the catalytic subunit isoform AMPK-α1 (but not α2) is cleaved by caspase-3 at an early...
5.
Thayyullathil F, Cheratta A, Alakkal A, Subburayan K, Pallichankandy S, Hannun Y, et al.
Cell Death Dis
. 2021 Jan;
12(1):26.
PMID: 33414455
Ferroptosis is a type of regulated cell death characterized by ROS accumulation and devastating lipid peroxidation (LPO). The role of acid sphingomyelinase (ASM), a key enzyme in sphingolipid metabolism, in...
6.
Cheratta A, Thayyullathil F, Pallichankandy S, Subburayan K, Alakkal A, Galadari S
Cell Death Dis
. 2021 Jan;
12(1):47.
PMID: 33414404
The tumor suppressor prostate apoptosis response-4 (Par-4) has recently turned 'twenty-five'. Beyond its indisputable role as an apoptosis inducer, an increasing and sometimes bewildering, new roles for Par-4 are being...
7.
Subburayan K, Thayyullathil F, Pallichankandy S, Cheratta A, Galadari S
Transl Oncol
. 2020 Aug;
13(11):100843.
PMID: 32805675
Ferroptosis is a novel form of programmed cell death characterized by an iron-dependent increase in reactive oxygen species (ROS). However, the role of ROS in the regulation of ferroptosis remains...
8.
Thayyullathil F, Cheratta A, Pallichankandy S, Subburayan K, Tariq S, Rangnekar V, et al.
Biochim Biophys Acta Mol Cell Res
. 2020 Mar;
1867(7):118692.
PMID: 32135176
Prostate apoptosis response-4 (Par-4) is a tumor suppressor protein that selectively induces apoptosis in cancer cells. Although the mechanism of Par-4-mediated induction of apoptosis has been well studied, the involvement...
9.
Rahman A, Pallichankandy S, Thayyullathil F, Galadari S
Free Radic Biol Med
. 2019 Feb;
134:527-544.
PMID: 30735839
Natural products are a major source of potential anticancer agents, and in order to develop improved and more effective cancer treatments, there is an immense need in exploring and elucidating...
10.
Subburayan K, Thayyullathil F, Pallichankandy S, Rahman A, Galadari S
Cancer Lett
. 2018 Apr;
426:80-97.
PMID: 29656006
Thymoquinone (TQ), the predominant bioactive constituent present in black cumin (Nigella sativa), exerts tumor suppressive activity against a wide variety of cancer cells. Cellular senescence, characterized by stable and long...