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Faisal J Alibhai

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Articles 41
Citations 572
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Recent Articles
1.
Lim A, Pouyabahar D, Ashraf M, Huang K, Lohbihler M, Murareanu B, et al.
Nat Commun . 2024 Nov; 15(1):10206. PMID: 39604360
The sinoatrial node regulates the heart rate throughout life. Failure of this primary pacemaker results in life-threatening, slow heart rhythm. Despite its critical function, the cellular and molecular composition of...
2.
Alibhai F, Tobin S
Methods Mol Biol . 2024 Sep; 2857:169-180. PMID: 39348065
Acute skeletal muscle injury initiates a process of necrosis, debris clearance, and ultimately tissue regeneration via myogenesis. While skeletal muscle stem cells (MuSCs) are responsible for populating the proliferative myogenic...
3.
Wulkan F, Romagnuolo R, Qiang B, Sadikov T, Kim K, Quesnel E, et al.
Front Cardiovasc Med . 2024 Jul; 11:1374881. PMID: 39045008
Background: Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) show tremendous promise for cardiac regeneration following myocardial infarction (MI), but their transplantation gives rise to transient ventricular tachycardia (VT) in large-animal MI...
4.
Shekari F, Alibhai F, Baharvand H, Borger V, Bruno S, Davies O, et al.
J Extracell Biol . 2024 Jun; 2(10):e115. PMID: 38939735
Cell culture-conditioned medium (CCM) is a valuable source of extracellular vesicles (EVs) for basic scientific, therapeutic and diagnostic applications. Cell culturing parameters affect the biochemical composition, release and possibly the...
5.
Khan S, Chakraborty M, Wu F, Chen N, Wang T, Chan Y, et al.
bioRxiv . 2024 Mar; PMID: 38529494
A dysregulated adaptive immune system is a key feature of aging, and is associated with age-related chronic diseases and mortality. Most notably, aging is linked to a loss in the...
6.
Alibhai F, Li R
Can J Cardiol . 2024 Mar; 40(8):1394-1411. PMID: 38460612
In Canada and worldwide, the elderly population (ie, individuals > 65 years of age) is increasing disproportionately relative to the total population. This is expected to have a substantial impact...
7.
Al-Attar R, Jargstorf J, Romagnuolo R, Jouni M, Alibhai F, Lampe P, et al.
Biomolecules . 2024 Jan; 14(1). PMID: 38254663
The transplantation of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) has shown promise in preclinical models of myocardial infarction, but graft myocardium exhibits incomplete host-graft electromechanical integration and a propensity for...
8.
Peng Z, Ludke A, Wu J, Li S, Alibhai F, Zhang Y, et al.
Stem Cells . 2024 Jan; 42(5):430-444. PMID: 38253331
It has been documented that the uterus plays a key cardio-protective role in pre-menopausal women, which is supported by uterine cell therapy, to preserve cardiac functioning post-myocardial infarction, being effective...
9.
Lee P, Hou L, Alibhai F, Al-Attar R, Simon-Chica A, Redondo-Rodriguez A, et al.
Front Cardiovasc Med . 2023 Jun; 10:1096884. PMID: 37283579
Scalable and high-throughput electrophysiological measurement systems are necessary to accelerate the elucidation of cardiac diseases in drug development. Optical mapping is the primary method of simultaneously measuring several key electrophysiological...
10.
Marvasti T, Alibhai F, Yang G, Li S, Wu J, Yau T, et al.
J Am Heart Assoc . 2023 Jun; 12(11):e027727. PMID: 37259988
Background Heart failure (HF) is a clinical syndrome associated with a progressive decline in myocardial function and low-grade systemic inflammation. Chronic inflammation can have lasting effects on the bone marrow...