Fabrizio Benedetti
Overview
Explore the profile of Fabrizio Benedetti including associated specialties, affiliations and a list of published articles.
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170
Citations
6156
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Recent Articles
1.
Benedetti F, Thoen W, Shaibani A, Arduino C
J Pain
. 2025 Jan;
28:104777.
PMID: 39805378
In order to disentangle the effects of drugs from placebo responses, several approaches have been used, such as a placebo run-in phase in which only placebo nonresponders, or poor responders,...
2.
Huber F, Arnaud M, Stevenson B, Michaux J, Benedetti F, Thevenet J, et al.
Nat Biotechnol
. 2024 Oct;
PMID: 39394480
The accurate identification and prioritization of antigenic peptides is crucial for the development of personalized cancer immunotherapies. Publicly available pipelines to predict clinical neoantigens do not allow direct integration of...
3.
Chiffelle J, Barras D, Petremand R, Orcurto A, Bobisse S, Arnaud M, et al.
Immunity
. 2024 Sep;
57(10):2466-2482.e12.
PMID: 39276771
Adoptive cell therapy (ACT) using in vitro expanded tumor-infiltrating lymphocytes (TILs) has inconsistent clinical responses. To better understand determinants of therapeutic success, we tracked TIL clonotypes from baseline tumors to...
4.
Frisaldi E, Ferrero B, Di Liberto A, Barbiani D, Camerone E, Piedimonte A, et al.
Muscle Nerve
. 2024 Jun;
70(3):413-419.
PMID: 38940302
Introduction/aims: The impact of treatment expectations on active treatment outcomes has not been specifically investigated in neuromuscular disorders. We thus explored in myasthenia gravis (MG) the contribution of patients' pre-treatment...
5.
Morotti M, Grimm A, Hope H, Arnaud M, Desbuisson M, Rayroux N, et al.
Nature
. 2024 Apr;
629(8011):426-434.
PMID: 38658764
Expansion of antigen-experienced CD8 T cells is critical for the success of tumour-infiltrating lymphocyte (TIL)-adoptive cell therapy (ACT) in patients with cancer. Interleukin-2 (IL-2) acts as a key regulator of...
6.
Barras D, Ghisoni E, Chiffelle J, Orcurto A, Dagher J, Fahr N, et al.
Sci Immunol
. 2024 Feb;
9(92):eadg7995.
PMID: 38306416
Adoptive cell therapy (ACT) using ex vivo-expanded tumor-infiltrating lymphocytes (TILs) can eliminate or shrink metastatic melanoma, but its long-term efficacy remains limited to a fraction of patients. Using longitudinal samples...
7.
Benedetti F, Arduino C, Shaibani A, Thoen W
J Pain
. 2023 Oct;
25(4):962-973.
PMID: 37907113
Conditioning and expectation are known to be the main mechanisms of placebo analgesia. They may operate together, so that expectations may be enhanced by a conditioning procedure. Although most of...
8.
Frisaldi E, Shaibani A, Benedetti F, Pagnini F
BMJ Open
. 2023 Oct;
13(10):e077243.
PMID: 37848293
Objectives: This review aimed to summarise the existing knowledge about placebo and nocebo effects associated with pharmacological interventions and their mechanisms. Design: Umbrella review, adopting the Assessment of Multiple Systematic...
9.
Bobisse S, Bianchi V, Tanyi J, Sarivalasis A, Missiaglia E, Petremand R, et al.
Nat Cancer
. 2023 Sep;
4(10):1410-1417.
PMID: 37735588
We have previously shown that vaccination with tumor-pulsed dendritic cells amplifies neoantigen recognition in ovarian cancer. Here, in a phase 1 clinical study ( NCT01312376 /UPCC26810) including 19 patients, we...
10.
Bill R, Wirapati P, Messemaker M, Roh W, Zitti B, Duval F, et al.
Science
. 2023 Aug;
381(6657):515-524.
PMID: 37535729
Tumor microenvironments (TMEs) influence cancer progression but are complex and often differ between patients. Considering that microenvironment variations may reveal rules governing intratumoral cellular programs and disease outcome, we focused...