Fabio Benigni
Overview
Explore the profile of Fabio Benigni including associated specialties, affiliations and a list of published articles.
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Articles
58
Citations
2615
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Recent Articles
1.
Isolation and escape mapping of broadly neutralizing antibodies against emerging delta-coronaviruses
Rexhepaj M, Asarnow D, Perruzza L, Park Y, Guarino B, Mccallum M, et al.
Immunity
. 2024 Nov;
57(12):2914-2927.e7.
PMID: 39488210
Porcine delta-coronavirus (PDCoV) spillovers were recently detected in febrile children, underscoring the recurrent zoonoses of divergent CoVs. To date, no vaccines or specific therapeutics are approved for use in humans...
2.
Rosen L, Tortorici M, De Marco A, Pinto D, Foreman W, Taylor A, et al.
Cell
. 2024 Oct;
187(25):7196-7213.e26.
PMID: 39383863
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) evolution has resulted in viral escape from clinically authorized monoclonal antibodies (mAbs), creating a need for mAbs that are resilient to epitope diversification....
3.
Rexhepaj M, Park Y, Perruzza L, Asarnow D, Mccallum M, Culap K, et al.
bioRxiv
. 2024 Apr;
PMID: 38617231
Porcine deltacoronavirus (PDCoV) spillovers were recently detected in children with acute undifferentiated febrile illness, underscoring recurrent zoonoses of divergent coronaviruses. To date, no vaccines or specific therapeutics are approved for...
4.
Addetia A, Piccoli L, Case J, Park Y, Beltramello M, Guarino B, et al.
Nature
. 2023 Aug;
621(7979):592-601.
PMID: 37648855
Currently circulating SARS-CoV-2 variants have acquired convergent mutations at hot spots in the receptor-binding domain (RBD) of the spike protein. The effects of these mutations on viral infection and transmission...
5.
Lempp F, Volz T, Cameroni E, Benigni F, Zhou J, Rosen L, et al.
J Hepatol
. 2023 Jul;
79(5):1129-1138.
PMID: 37459920
Background & Aims: Chronic hepatitis B is a global public health problem, and coinfection with hepatitis delta virus (HDV) worsens disease outcome. Here, we describe a hepatitis B virus (HBV)...
6.
Park Y, Pinto D, Walls A, Liu Z, De Marco A, Benigni F, et al.
Science
. 2022 Oct;
378(6620):619-627.
PMID: 36264829
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sublineages carry distinct spike mutations resulting in escape from antibodies induced by previous infection or vaccination. We show that hybrid immunity or...
7.
Low J, Jerak J, Tortorici M, McCallum M, Pinto D, Cassotta A, et al.
Science
. 2022 Jul;
377(6607):735-742.
PMID: 35857703
The coronavirus spike glycoprotein attaches to host receptors and mediates viral fusion. Using a broad screening approach, we isolated seven monoclonal antibodies (mAbs) that bind to all human-infecting coronavirus spike...
8.
Park Y, Pinto D, Walls A, Liu Z, De Marco A, Benigni F, et al.
bioRxiv
. 2022 Jun;
PMID: 35677069
SARS-CoV-2 Omicron sublineages carry distinct spike mutations and represent an antigenic shift resulting in escape from antibodies induced by previous infection or vaccination. We show that hybrid immunity or vaccine...
9.
Costello C, Willsey G, Richards A, Kim J, Pizzuto M, Jaconi S, et al.
Infect Immun
. 2022 May;
90(6):e0004122.
PMID: 35579465
Secretory IgA (SIgA) is the most abundant antibody type in intestinal secretions where it contributes to safeguarding the epithelium from invasive pathogens like the Gram-negative bacterium, Salmonella enterica serovar Typhimurium...
10.
Park Y, De Marco A, Starr T, Liu Z, Pinto D, Walls A, et al.
Science
. 2022 Jan;
375(6579):449-454.
PMID: 34990214
Understanding broadly neutralizing sarbecovirus antibody responses is key to developing countermeasures against SARS-CoV-2 variants and future zoonotic sarbecoviruses. We describe the isolation and characterization of a human monoclonal antibody, designated...