Fabienne Foufelle
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Explore the profile of Fabienne Foufelle including associated specialties, affiliations and a list of published articles.
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92
Citations
5683
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Recent Articles
1.
Le Goff W, Bourron O, Materne C, Galier S, Phan F, Tan-Chen S, et al.
Cardiovasc Diabetol
. 2025 Feb;
24(1):85.
PMID: 39984928
Background: Sphingosine 1-phosphate (S1P) is a key mediator of lipid signaling with strong immunomodulatory and anti-inflammatory effects. Circulating S1P levels including S1P in high-density lipoproteins (HDL) were demonstrated to be...
2.
Phan F, Bourron O, Foufelle F, Le Stunff H, Hajduch E
FEBS Lett
. 2024 Jul;
598(21):2641-2655.
PMID: 38965662
Cardiometabolic disorders contribute to the global burden of cardiovascular diseases. Emerging sphingolipid metabolites like sphingosine-1-phosphate (S1P) and its receptors, S1PRs, present a dynamic signalling axis significantly impacting cardiac homeostasis. S1P's...
3.
Denimal D, Ponnaiah M, Jeannin A, Phan F, Hartemann A, Boussouar S, et al.
Cardiovasc Diabetol
. 2024 Feb;
23(1):69.
PMID: 38351039
Background: Studies have demonstrated that coronary artery calcification on one hand and non-alcoholic fatty liver disease (NAFLD) on the other hand are strongly associated with cardiovascular events. However, it remains...
4.
Lallement J, Raho I, Merlen G, Rainteau D, Croyal M, Schiffano M, et al.
Biochim Biophys Acta Mol Cell Biol Lipids
. 2023 May;
1868(8):159333.
PMID: 37224999
Ceramides (Cer) have been shown as lipotoxic inducers, which disturb numerous cell-signaling pathways, leading to metabolic disorders such as type 2 diabetes. In this study, we aimed to determine the...
5.
Hazari Y, Urra H, Garcia Lopez V, Diaz J, Tamburini G, Milani M, et al.
bioRxiv
. 2023 May;
PMID: 37205565
Collagen is one the most abundant proteins and the main cargo of the secretory pathway, contributing to hepatic fibrosis and cirrhosis due to excessive deposition of extracellular matrix. Here we...
6.
Bandet C, Tan-Chen S, Ali-Berrada S, Campana M, Poirier M, Blachnio-Zabielska A, et al.
J Biol Chem
. 2023 May;
299(6):104815.
PMID: 37178918
Ceramides have been shown to play a major role in the onset of skeletal muscle insulin resistance and therefore in the prevalence of type 2 diabetes. However, many of the...
7.
Palacios-Ramirez R, Lima-Posada I, Bonnard B, Genty M, Fernandez-Celis A, Hartleib-Geschwindner J, et al.
Front Physiol
. 2022 Apr;
13:859812.
PMID: 35464084
Obesity and/or metabolic diseases are frequently associated with chronic kidney disease and several factors associated with obesity may contribute to proteinuria and extracellular matrix production. Mineralocorticoid receptor antagonists have proven...
8.
Ferre P, Phan F, Foufelle F
Biochem J
. 2021 Oct;
478(20):3723-3739.
PMID: 34673919
Sterol Regulatory Element Binding Protein-1c is a transcription factor that controls the synthesis of lipids from glucose in the liver, a process which is of utmost importance for the storage...
9.
Lefranc C, Friederich-Persson M, Foufelle F, Nguyen Dinh Cat A, Jaisser F
Int J Mol Sci
. 2021 Apr;
22(6).
PMID: 33809055
Mineralocorticoid receptor (MR) expression is increased in the adipose tissue (AT) of obese patients and animals. We previously demonstrated that adipocyte-MR overexpression in mice (Adipo-MROE mice) is associated with metabolic...
10.
Hajduch E, Lachkar F, Ferre P, Foufelle F
J Clin Med
. 2021 Mar;
10(4).
PMID: 33669443
Non-alcoholic fatty liver disease is one of the most common chronic liver diseases, ranging from simple steatosis to steatohepatitis, fibrosis, and cirrhosis. Its prevalence is rapidly increasing and presently affects...