Fabian Sesterhenn
Overview
Explore the profile of Fabian Sesterhenn including associated specialties, affiliations and a list of published articles.
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Articles
21
Citations
771
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Recent Articles
1.
Csepregi L, Hoehn K, Neumeier D, Taft J, Friedensohn S, Weber C, et al.
Elife
. 2024 Dec;
13.
PMID: 39693231
Diverse antibody repertoires spanning multiple lymphoid organs (i.e., bone marrow, spleen, lymph nodes) form the foundation of protective humoral immunity. Changes in their composition across lymphoid organs are a consequence...
2.
Stoeckli M, Wang H, Staab D, Grandjean F, Sesterhenn F, Opitz C
SLAS Technol
. 2024 Oct;
29(6):100216.
PMID: 39454874
Tracking chemical reactions by measuring incurred mass shifts upon successful binding is a direct and attractive alternative to existing assays based on chemical tags. Traditional methods use liquid chromatography-mass spectrometry...
3.
Schiffner T, Phung I, Ray R, Irimia A, Tian M, Swanson O, et al.
Nat Immunol
. 2024 Jun;
25(7):1307.
PMID: 38877179
No abstract available.
4.
Schiffner T, Phung I, Ray R, Irimia A, Tian M, Swanson O, et al.
Nat Immunol
. 2024 May;
25(6):1073-1082.
PMID: 38816615
A key barrier to the development of vaccines that induce broadly neutralizing antibodies (bnAbs) against human immunodeficiency virus (HIV) and other viruses of high antigenic diversity is the design of...
5.
Holfeld A, Schuster D, Sesterhenn F, Gillingham A, Stalder P, Haenseler W, et al.
Mol Syst Biol
. 2024 May;
20(6):651-675.
PMID: 38702390
The physical interactome of a protein can be altered upon perturbation, modulating cell physiology and contributing to disease. Identifying interactome differences of normal and disease states of proteins could help...
6.
Cremosnik G, Mesrouze Y, Zueger P, Furkert D, Grandjean F, Argoti D, et al.
ACS Chem Biol
. 2024 Apr;
19(5):1142-1150.
PMID: 38655884
The ARID1A and ARID1B subunits are mutually exclusive components of the BAF variant of SWI/SNF chromatin remodeling complexes. Loss of function mutations in ARID1A are frequently observed in various cancers,...
7.
Mermet-Meillon F, Mercan S, Bauer-Probst B, Allard C, Bleu M, Calkins K, et al.
Nat Struct Mol Biol
. 2024 Feb;
31(7):1018-1022.
PMID: 38347147
ARID1B is a SWI/SNF subunit frequently mutated in human Coffin-Siris syndrome (CSS) and it is necessary for proliferation of ARID1A mutant cancers. While most CSS ARID1B aberrations introduce frameshifts or...
8.
Malinovska L, Cappelletti V, Kohler D, Piazza I, Tsai T, Pepelnjak M, et al.
Nat Protoc
. 2023 Jan;
18(6):1979.
PMID: 36653529
No abstract available.
9.
Malinovska L, Cappelletti V, Kohler D, Piazza I, Tsai T, Pepelnjak M, et al.
Nat Protoc
. 2022 Dec;
18(3):659-682.
PMID: 36526727
Proteins regulate biological processes by changing their structure or abundance to accomplish a specific function. In response to a perturbation, protein structure may be altered by various molecular events, such...
10.
Harteveld Z, Bonet J, Rosset S, Yang C, Sesterhenn F, Correia B
Proc Natl Acad Sci U S A
. 2022 Oct;
119(43):e2206111119.
PMID: 36252041
De novo protein design enables the exploration of novel sequences and structures absent from the natural protein universe. De novo design also stands as a stringent test for our understanding...