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F R Carbone

Explore the profile of F R Carbone including associated specialties, affiliations and a list of published articles. Areas
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Articles 78
Citations 5987
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Recent Articles
1.
Frizzell H, Fonseca R, Christo S, Evrard M, Cruz-Gomez S, Zanluqui N, et al.
Sci Immunol . 2020 Apr; 5(46). PMID: 32245887
Tissue-resident memory T (T) cells exist throughout the body, where they are poised to mediate local immune responses. Although studies have defined a common mechanism of residency independent of location,...
2.
Heath W, Carbone F
Nat Rev Immunol . 2002 Mar; 1(2):126-34. PMID: 11905820
T lymphocytes recognize peptide antigens presented by class I and class II molecules encoded by the major histocompatibility complex (MHC). Classical antigen-presentation studies showed that MHC class I molecules present...
3.
Villadangos J, Cardoso M, Steptoe R, van Berkel D, Pooley J, Carbone F, et al.
Immunity . 2001 Jun; 14(6):739-49. PMID: 11420044
We have investigated the mechanisms that control MHC class II (MHC II) expression in immature and activated dendritic cells (DC) grown from spleen and bone marrow precursors. Degradation of the...
4.
Camacho S, Heath W, Carbone F, Sarvetnick N, Lebon A, Karlsson L, et al.
Nat Immunol . 2001 May; 2(6):523-9. PMID: 11376339
We investigated how the accessory molecule interactions encountered during T cell priming influence T cell-mediated destruction of insulin-producing beta cells and lead to type 1 diabetes. T cell receptor (TCR)-transgenic...
5.
Li M, Davey G, Sutherland R, Kurts C, Lew A, Hirst C, et al.
J Immunol . 2001 May; 166(10):6099-103. PMID: 11342628
To better understand the antigenic requirements for cross-presentation, we compared the in vivo efficiency of presentation of cell-associated vs soluble OVA with the OT-I (CD8) and OT-II (CD4) TCR transgenic...
6.
Heath W, Carbone F
Annu Rev Immunol . 2001 Mar; 19:47-64. PMID: 11244030
This review examines the role of cross-presentation in tolerance and immunity. We discuss (a) the antigenic requirements for cross-presentation, (b) the phenotype of the antigen presenting cell (APC), (c) the...
7.
Wallace M, Bryden M, Cose S, COLES R, Schumacher T, Brooks A, et al.
Immunity . 2000 Jun; 12(5):547-56. PMID: 10843387
The enormous diversity of the T cell pool makes it difficult to determine whether inherent biases in the naive TCR repertoire can influence T cell responsiveness. In C57BL/6 mice the...
8.
Clarke S, Barnden M, Kurts C, Carbone F, Miller J, Heath W
Immunol Cell Biol . 2000 Apr; 78(2):110-7. PMID: 10762410
The present report provides the first extensive characterization of the OT-I TCR transgenic line, which produces MHC class I-restricted, ovalbumin-specific, CD8+ T cells (OT-I cells). These cells are shown to...
9.
Blanas E, Davey G, Carbone F, Heath W
J Immunol . 2000 Mar; 164(6):2890-6. PMID: 10706674
We have previously reported that feeding OVA to C57BL/6 mice can lead to a weak CTL response that is dependent on CD4+ T cell help and is capable of causing...
10.
Jones C, Cose S, COLES R, Winterhalter A, Brooks A, Heath W, et al.
J Virol . 2000 Feb; 74(5):2414-9. PMID: 10666272
Various studies have shown that major histocompatibility complex class I-restricted cytotoxic T lymphocytes (CTL) can be isolated from lymph nodes draining sites of cutaneous infection with herpes simplex virus type...