F Okajima
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Explore the profile of F Okajima including associated specialties, affiliations and a list of published articles.
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102
Citations
1440
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Recent Articles
1.
Chiba M, Ohmichi M, Inaba Y, Okajima F, Araki S, Murata K, et al.
Environ Health Prev Med
. 2011 Mar;
3(4):223-7.
PMID: 21432530
No abstract available.
2.
Sugihara H, Shibasaki T, Tatsuguchi A, Okajima F, Wakita S, Nakajima Y, et al.
J Endocrinol Invest
. 2007 Jun;
30(5):421-7.
PMID: 17598976
Cases of acromegaly due to GHRHproducing pancreatic endocrine tumors have been reported. Here we present a case of a 31-yr-old nonacromegalic man with hyperparathyroidism and elevated serum IGF-I with normal...
3.
Okajima F
Nihon Yakurigaku Zasshi
. 2002 Jan;
118(6):383-8.
PMID: 11778456
Sphingosine 1-phosphate (S1P), one of the sphingolipid metabolites, has been shown to participate in a variety of cellular responses including proliferation, differentiation, adhesion, motility, and apoptosis. These cellular responses elicited...
4.
Tosaka M, Okajima F, Hashiba Y, Saito N, Nagano T, Watanabe T, et al.
Stroke
. 2001 Dec;
32(12):2913-9.
PMID: 11739995
Background And Purpose: Sphingosine 1-phosphate (S1P) is a platelet-derived bioactive lipid that exerts a variety of biological responses, including vasocontraction. To understand the involvement of S1P in cerebral vasospasm, we...
5.
Sawada Y, Zhang B, Okajima F, Izumi T, Takeuchi T
Mol Cell Endocrinol
. 2001 Aug;
182(2):265-75.
PMID: 11514060
Parathyroid hormone-related protein (PTHrP) is reportedly produced in normal islets and insulinomas. PTHrP induces differentiation in some cell-types and growth in others. We examined whether PTHrP production is greater in...
6.
Ishizuka T, Okajima F, ISHIWARA M, Iizuka K, Ichimonji I, Kawata T, et al.
J Immunol
. 2001 Aug;
167(4):2298-304.
PMID: 11490018
Although mast cells accumulate within the mucosal epithelial layer of patients with allergic rhinitis and bronchial asthma, the responsible chemotactic factors are undefined. We investigated whether mast cells sensitized with...
7.
Kimura T, Sato K, Kuwabara A, Tomura H, ISHIWARA M, Kobayashi I, et al.
J Biol Chem
. 2001 Jun;
276(34):31780-5.
PMID: 11427538
Sphingosine 1-phosphate (S1P), a novel lipid mediator, is concentrated in the fraction of lipoproteins that include high density lipoprotein (HDL) and low density lipoprotein (LDL) in human plasma. Here, we...
8.
Sato K, Ui M, Okajima F
Brain Res Mol Brain Res
. 2001 Jan;
85(1-2):151-60.
PMID: 11146117
Several cDNA encoding G-protein-coupled receptors, i.e. Edg-1,-3,-5,-6 and -8, have recently been identified as sphingosine 1-phosphate (S1P) receptors. However, the role of the respective receptor subtype has not been well...
9.
Tamama K, Kon J, Sato K, Tomura H, Kuwabara A, Kimura T, et al.
Biochem J
. 2000 Dec;
353(Pt 1):139-146.
PMID: 11115407
Exogenous sphingosine 1-phosphate (S1P) increased cytosolic Ca(2+) concentration, stimulated thymidine incorporation (DNA synthesis) and inhibited cell migration in rat aortic smooth-muscle cells (AoSMCs). Although exogenous sphingosine, a substrate of sphingosine...
10.
Murata N, Sato K, Kon J, Tomura H, Yanagita M, Kuwabara A, et al.
Biochem J
. 2000 Dec;
352 Pt 3:809-15.
PMID: 11104690
The concentration of sphingosine 1-phosphate (S1P) in plasma or serum is much higher than the half-maximal concentration of the sphingolipid needed to stimulate its receptors. Nevertheless, the inositol phosphate response...