F Nuckolls
Overview
Explore the profile of F Nuckolls including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
1197
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Recent Articles
1.
Wu L, Timmers C, Maiti B, Saavedra H, Sang L, Chong G, et al.
Nature
. 2001 Nov;
414(6862):457-62.
PMID: 11719808
The retinoblastoma tumour suppressor (Rb) pathway is believed to have a critical role in the control of cellular proliferation by regulating E2F activities. E2F1, E2F2 and E2F3 belong to a...
2.
Leone G, Sears R, Huang E, Rempel R, Nuckolls F, Park C, et al.
Mol Cell
. 2001 Aug;
8(1):105-13.
PMID: 11511364
Previous work has shown that the Myc transcription factor induces transcription of the E2F1, E2F2, and E2F3 genes. Using primary mouse embryo fibroblasts deleted for individual E2F genes, we now...
3.
Sears R, Nuckolls F, Haura E, Taya Y, Tamai K, Nevins J
Genes Dev
. 2000 Oct;
14(19):2501-14.
PMID: 11018017
Our recent work has shown that activation of the Ras/Raf/ERK pathway extends the half-life of the Myc protein and thus enhances the accumulation of Myc activity. We have extended these...
4.
Adams M, Sears R, Nuckolls F, Leone G, Nevins J
Mol Cell Biol
. 2000 Apr;
20(10):3633-9.
PMID: 10779353
E2F transcription activity has been shown to play a critical role in cell growth control, regulating the expression of a variety of genes that encode proteins important for the initiation...
5.
Leone G, Nuckolls F, Ishida S, Adams M, Sears R, Jakoi L, et al.
Mol Cell Biol
. 2000 Apr;
20(10):3626-32.
PMID: 10779352
The tumor suppressor function of Rb is intimately related to its ability to interact with E2F and repress the transcription of E2F target genes. Here we describe a novel E2F...