F N Ziyadeh
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Explore the profile of F N Ziyadeh including associated specialties, affiliations and a list of published articles.
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113
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2717
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Recent Articles
1.
Abou Msallem J, Chalhoub H, Al-Hariri M, Saad L, Jaffa M, Ziyadeh F, et al.
Am J Physiol Renal Physiol
. 2015 Oct;
309(11):F980-90.
PMID: 26447218
Diabetic nephropathy (DN) is the main cause of morbidity and mortality in diabetes and is characterized by mesangial matrix deposition and podocytopathy, including podocyte loss. The risk factors and mechanisms...
2.
Ziyadeh F, Isono M, Chen S
Clin Exp Nephrol
. 2014 Jul;
6(3):125-9.
PMID: 24989950
The manifestation of diabetic nephropathy may be a consequence of the actions of certain cytokines and growth factors. Prominent among them is transforming growth factor-β (TGF-β), which promotes renal cell...
3.
Eid S, Abou-Kheir W, Sabra R, Daoud G, Jaffa A, Ziyadeh F, et al.
J Biol Regul Homeost Agents
. 2013 Oct;
27(3):693-703.
PMID: 24152838
Diabetic nephropathy (DN) is one of the most serious complications of type I and type II diabetes. DN is characterized by hyperfiltration, hypertrophy, extracellular matrix accumulation, and proteinuria. This advances...
4.
Moreno-Manzano V, Mampaso F, Sepulveda-Munoz J, Alique M, Chen S, Ziyadeh F, et al.
Br J Pharmacol
. 2003 Jun;
139(4):823-31.
PMID: 12813006
1 Puromycin aminonucleoside (PAN)-induced nephrosis is a model of human minimal change disease. In rats, PAN induces nephrotic-range proteinuria, renal epithelial cell (podocyte) damage, infiltration of mononuclear leukocytes, and apoptosis...
5.
Chen S, Wolf G, Ziyadeh F
Contrib Nephrol
. 2001 Nov;
(135):212-21.
PMID: 11705286
No abstract available.
6.
Chen S, Hong S, Iglesias-de la Cruz M, Isono M, Casaretto A, Ziyadeh F
Ren Fail
. 2001 Aug;
23(3-4):471-81.
PMID: 11499562
Progressive renal injury in diabetes mellitus leads to major morbidity and mortality. The manifestations of diabetic nephropathy may be a consequence of the actions of certain cytokines and growth factors....
7.
Goldfarb S, Ziyadeh F
Trans Am Clin Climatol Assoc
. 2001 Jun;
112:27-32; discussion 33.
PMID: 11413780
In summary, metabolic, hemodynamic, and genetic factors are all important in the development and progression of diabetic nephropathy (33). Recent studies using cell culture techniques and experimental animal models have...
8.
Hong S, Isono M, Chen S, Iglesias-de la Cruz M, Han D, Ziyadeh F
Am J Pathol
. 2001 May;
158(5):1653-63.
PMID: 11337363
Activation of the renal transforming growth factor-beta (TGF-beta) system likely mediates the excess production of extracellular matrix in the diabetic kidney. To establish the role of the TGF-beta system in...
9.
Han D, Isono M, Chen S, Casaretto A, Hong S, Wolf G, et al.
Kidney Int
. 2001 Mar;
59(4):1315-23.
PMID: 11260392
Background: Serum leptin levels correlate with fat cell mass and are elevated in patients with massive obesity and type 2 diabetes mellitus, which are strong risk factors for the development...
10.
Chen S, Cohen M, Lautenslager G, Shearman C, Ziyadeh F
Kidney Int
. 2001 Feb;
59(2):673-81.
PMID: 11168949
Background: The activation of protein kinase C (PKC) and transforming growth factor-beta (TGF-beta) in glomerular mesangial cells has been linked to mesangial matrix expansion in diabetic nephropathy. The role of...