F K Ghishan
Overview
Explore the profile of F K Ghishan including associated specialties, affiliations and a list of published articles.
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Articles
169
Citations
1000
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Recent Articles
1.
Larmonier C, Shehab K, Ghishan F, Kiela P
Biomed Res Int
. 2015 Nov;
2015:504638.
PMID: 26583115
Humans have coevolved with a complex community of bacterial species also referred to as the microbiome, which reciprocally provides critical contributions to human metabolism and immune system development. Gut microbiome...
2.
Larmonier C, McFadden R, Hill F, Schreiner R, Ramalingam R, Besselsen D, et al.
Am J Physiol Gastrointest Liver Physiol
. 2013 May;
305(1):G35-46.
PMID: 23639807
Decreased bone mineral density (BMD) represents an extraintestinal complication of inflammatory bowel disease (IBD). Vitamin D₃ has been considered a viable adjunctive therapy in IBD. However, vitamin D₃ plays a...
3.
Larmonier C, Laubitz D, Thurston R, Bucknam A, Hill F, Midura-Kiela M, et al.
Am J Physiol Gastrointest Liver Physiol
. 2011 Mar;
300(6):G998-G1009.
PMID: 21415416
NHE3, the major intestinal Na(+)/H(+) exchanger, was shown to be downregulated and/or inhibited in patients with inflammatory bowel disease (IBD), a phenomenon believed to contribute to inflammation-associated diarrhea. NHE3(-/-) mice...
4.
Larmonier C, Midura-Kiela M, Ramalingam R, Laubitz D, Janikashvili N, Larmonier N, et al.
Inflamm Bowel Dis
. 2010 Jul;
17(2):503-15.
PMID: 20629184
Background: Neutrophils (PMN) are the first cells recruited at the site of inflammation. They play a key role in the innate immune response by recognizing, ingesting, and eliminating pathogens and...
5.
Larmonier C, Uno J, Lee K, Karrasch T, Laubitz D, Thurston R, et al.
Am J Physiol Gastrointest Liver Physiol
. 2008 Sep;
295(5):G1079-91.
PMID: 18818316
Curcumin (diferulolylmethane) demonstrates profound anti-inflammatory effects in intestinal epithelial cells (IEC) and in immune cells in vitro and exhibits a protective role in rodent models of chemically induced colitis, with...
6.
Kiela P, Xu H, Ghishan F
J Physiol Pharmacol
. 2007 Jan;
57 Suppl 7:51-79.
PMID: 17228096
The Slc9a family of nine Na(+)/H(+) exchangers (NHE) plays a critical role in neutral sodium absorption in the mammalian intestine as well as other absorptive and secretory epithelia of digestive...
7.
Bai L, Collins J, Xu H, Xu L, Ghishan F
Biochim Biophys Acta
. 2001 Nov;
1522(1):42-5.
PMID: 11718898
We report the novel cloning and preliminary characterization of a murine type III sodium-dependent phosphate cotransporter (Pit-2) gene promoter. Five promoter/luciferase reporter gene constructs, -1816/+61, -1620/+61, -1223/+61, -600/+61 and -225/+61,...
8.
Kiela P, Hines E, Collins J, Ghishan F
Am J Physiol Gastrointest Liver Physiol
. 2001 Sep;
281(4):G947-56.
PMID: 11557515
Short-chain fatty acids, and especially butyrate (NaB), stimulate sodium and water absorption by inducing colonic Na+/H+ exchange (NHE). NaB induces NHE3 activity and protein and mRNA expression both in vivo...
9.
Xu H, Collins J, Bai L, Kiela P, Lynch R, Ghishan F
Am J Physiol Cell Physiol
. 2001 Jul;
281(2):C504-13.
PMID: 11443049
Epidermal growth factor (EGF) is involved in acute regulation of Na(+)/H(+) exchangers (NHEs), but the effect of chronic EGF administration on NHE gene expression is unknown. The present studies showed...
10.
Bai L, Xu H, Collins J, Ghishan F
J Biol Chem
. 2001 Jul;
276(39):36764-9.
PMID: 11432869
Glutamate is the major excitatory neurotransmitter in the mammalian central nervous system. Packaging and storage of glutamate into glutamatergic neuronal vesicles requires ATP-dependent vesicular glutamate uptake systems, which utilize the...