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F Carlassare

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Articles 57
Citations 75
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Recent Articles
1.
Marzano C, Chilin A, Guiotto A, Baccichetti F, Carlassare F, Bordin F
Farmaco . 2001 Jan; 55(9-10):650-8. PMID: 11152248
A new furoquinolinone derivative, 1-(3'-hydroxypropyl)-4,6,8-trimethylfuro[2,3-h]quinolin-2(1H)-one (HPFQ, 4), was prepared, in which the nitrogen atom in position 1 carries a hydroxypropyl chain. The antiproliferative activity of HPFQ was studied in comparison...
2.
Marzano C, Baccichetti F, Carlassare F, Chilin A, Lora S, Bordin F
Photochem Photobiol . 2000 Mar; 71(3):263-72. PMID: 10732443
4,6,8,9-Tetramethyl-2H-furo[2,3-h]quinolin-2-one (HFQ) and its isomer FQ (1,4,6,8-tetramethyl-2H-furo[2,3-h]quinolin-2-one) showed very strong antiproliferative activity in mammalian cells, about two times greater than 8-methoxypsoralen (8-MOP). Both compounds induced DNA-protein cross-links (DPC) but not...
3.
Bordin F, Baccichetti F, Marzano C, Carlassare F, Miolo G, Chilin A, et al.
Photochem Photobiol . 2000 Mar; 71(3):254-62. PMID: 10732442
Some photochemical and photobiological properties of 4,6,8,9-tetramethyl-2H-furo[2,3-h]quinolin-2-one (HFQ) were studied in comparison with its isomer 1,4,6,8-tetramethyl-2H-furo[2,3-h]quinolin-2-one (FQ) and 8-methoxypsoralen (8-MOP). The HFQ photobinds to DNA forming furan-side monoadducts (MAHFQ) that...
4.
Chilin A, Marzano C, Guiotto A, Manzini P, Baccichetti F, Carlassare F, et al.
J Med Chem . 1999 Jul; 42(15):2936-45. PMID: 10425103
Some benzopsoralens, carrying a hydroxymethyl or a diethylaminomethyl group at the 3, 5, 8, and 11 positions, were prepared, and their biological activity was compared with that of 4-(hydroxymethyl)benzopsoralen (BP)....
5.
Ferlin M, Chiarelotto G, Marzano C, Severin E, Baccichetti F, Carlassare F, et al.
Farmaco . 1998 Oct; 53(6):431-7. PMID: 9764477
A series of methyl and ethyl quaternary pyridiniumtetrahydrocarbazoles was synthesized and studied in comparison with ellipticine, chosen as a reference. In general, their antiproliferative activity, tested in different biological substrates,...
6.
Bordin F, Marzano C, Baccichetti F, Carlassare F, Vedaldi D, Falcomer S, et al.
Photochem Photobiol . 1998 Sep; 68(2):157-63. PMID: 9723209
Some photobiological properties of 1'-thieno-4,6,4'-trimethylangelicin (TTMA), a new isoster of 4,6,4'-trimethylangelicin (TMA) were studied in comparison with the parent compound. The TTMA absorbs UVA light and photobinds in vitro to...
7.
Baccichetti F, Marzano C, Carlassare F, Guiotto A, Bordin F
J Photochem Photobiol B . 1998 Feb; 40(3):299-304. PMID: 9372620
The capacity of 2,6-dimethyl-9-methoxy-4H-pyrrolo [3,2,1-ij] quinolin-4-one (PQ), a furocoumarin analogue, of inhibiting protein synthesis in Ehrlich cells upon UVA irradiation was investigated. Using 8-methoxypsoralen (8-MOP) as a reference, we observed...
8.
Rodighiero P, Chilin A, Guiotto A, Marzano C, Baccichetti F, Carlassare F, et al.
Farmaco . 1997 Jan; 52(1):7-12. PMID: 9181674
The synthesis of 2H-benzopyrano[7,8-b][1,4]tetrahydrobenzodioxin-2-ones and 2H-benzopyrano [7,8-b][1,4]benzodioxin-2-ones is reported. This class of compounds, prepared with the aim of obtaining new monofunctional photosensitizing drug, appears to be ineffective upon UVA irradiation...
9.
Bordin F, Marzano C, Carlassare F, Rodighiero P, Guiotto A, Caffieri S, et al.
J Photochem Photobiol B . 1996 Jul; 34(2-3):159-68. PMID: 8810533
1,4,6,8-tetramethyl-2H-furo[2,3-h]quinolin-2-one (FQ) is a new isoster of angelicin characterised by an extremely strong photosensitizing activity, which is several times higher than that of 8-MOP and 4,6,4'-trimethylangelicin (TMA). Following treatment with...
10.
Rodighiero P, Guiotto A, Chilin A, Bordin F, Baccichetti F, Carlassare F, et al.
J Med Chem . 1996 Mar; 39(6):1293-302. PMID: 8632436
With the aim of obtaining new potential photochemotherapeutic agents, having increased antiproliferative activity and decreased undesired effects, we have prepared some new furoquinolinones. Two of them have been studied in...