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F C Abogadie

Explore the profile of F C Abogadie including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 840
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Recent Articles
1.
Grace M, Lieu T, Darby B, Abogadie F, Veldhuis N, Bunnett N, et al.
Br J Pharmacol . 2014 May; 171(16):3881-94. PMID: 24779362
Background And Purpose: Protease-activated receptor 2 (PAR2) is expressed on nociceptive neurons, and can sensitize transient receptor potential (TRP) ion channels to amplify neurogenic inflammation and pain. The mechanisms by...
2.
Abogadie F, Bron R, Marsh S, DREW L, Haley J, Buckley N, et al.
Neuropharmacology . 2002 Jun; 42(7):950-7. PMID: 12069905
Antisense approaches are increasingly used to dissect signaling pathways linking cell surface receptors to intracellular effectors. Here we used a recombinant adenovirus to deliver G-protein alpha(q) antisense into rat superior...
3.
Abogadie F, Milligan G, Delmas P, Brown D
Eur J Neurosci . 2001 Sep; 14(2):283-92. PMID: 11553279
Although many G-protein-coupled neurotransmitter receptors are potentially capable of modulating both voltage-dependent Ca(2+) channels (I(Ca)) and G-protein-gated K(+) channels (I(GIRK)), there is a substantial degree of selectivity in the coupling...
4.
Tatulian L, Delmas P, Abogadie F, Brown D
J Neurosci . 2001 Jul; 21(15):5535-45. PMID: 11466425
Retigabine [D-23129; N-(2-amino-4-(4-fluorobenzylamino)-phenyl) carbamic acid ethyl ester] is a novel anticonvulsant compound that is now in clinical phase II development. It has previously been shown to enhance currents generated by...
5.
Haley J, Abogadie F, Dayrell M, Vallis Y, Buckley N, Brown D
J Neurosci . 2000 Oct; 20(21):RC105. PMID: 11050147
Rat superior cervical ganglion (SCG) neurons express low-threshold noninactivating M-type potassium channels (I(K(M))), which can be inhibited by activation of M(1) muscarinic receptors (M(1) mAChR) and bradykinin (BK) B(2) receptors....
6.
Delmas P, Abogadie F, Buckley N, Brown D
Nat Neurosci . 2000 Jun; 3(7):670-8. PMID: 10862699
Voltage-gated Ca2+ channels participate in dendritic integration, yet functional properties of Ca2+ channels and mechanisms of their modulation by neurotransmitters in dendrites are unknown. Here we report how pharmacologically identified...
7.
Haley J, Delmas P, Offermanns S, Abogadie F, Simon M, Buckley N, et al.
J Neurosci . 2000 May; 20(11):3973-9. PMID: 10818132
Activation of M(1) muscarinic acetylcholine receptors (M(1) mAChR) inhibits M-type potassium currents (I(K(M))) and N-type calcium currents (I(Ca)) in mammalian sympathetic ganglia. Previous antisense experiments suggested that, in rat superior...
8.
Selyanko A, Hadley J, Wood I, Abogadie F, Jentsch T, Brown D
J Physiol . 2000 Mar; 522 Pt 3:349-55. PMID: 10713961
1. KCNQ1-4 potassium channels were expressed in mammalian Chinese hamster ovary (CHO) cells stably transfected with M1 muscarinic acetylcholine receptors and currents were recorded using the whole-cell perforated patch technique...
9.
Hadley J, Noda M, Selyanko A, Wood I, Abogadie F, Brown D
Br J Pharmacol . 2000 Mar; 129(3):413-5. PMID: 10711337
In Shaker-group potassium channels the presence of a tyrosine residue, just downstream of the pore signature sequence GYG, determines sensitivity to tetraethylammonium (TEA). The KCNQ family of channels has a...
10.
White H, McCabe R, Armstrong H, Donevan S, Cruz L, Abogadie F, et al.
J Pharmacol Exp Ther . 1999 Dec; 292(1):425-32. PMID: 10604979
The purification, characterization, and synthesis of conantokin-R (Con-R), an N-methyl-D-aspartate (NMDA) receptor peptide antagonist from the venom of Conus radiatus, are described. With the use of well defined animal seizure...