B de Massy
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Explore the profile of B de Massy including associated specialties, affiliations and a list of published articles.
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19
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1587
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Recent Articles
1.
Robert T, Nore A, Brun C, Maffre C, Crimi B, Bourbon H, et al.
Science
. 2016 Feb;
351(6276):943-9.
PMID: 26917764
Meiotic recombination is induced by the formation of DNA double-strand breaks (DSBs) catalyzed by SPO11, the ortholog of subunit A of TopoVI DNA topoisomerase (TopoVIA). TopoVI activity requires the interaction...
2.
Romero Y, Vuandaba M, Suarez P, Grey C, Calvel P, Conne B, et al.
Sex Dev
. 2012 May;
6(4):169-77.
PMID: 22571926
Spermatogenesis relies on the precise regulation of the self-renewal and differentiation of spermatogonia to provide a continuous supply of differentiating germ cells. The understanding of the cellular pathways regulating this...
3.
Baudat F, Buard J, Grey C, Fledel-Alon A, Ober C, Przeworski M, et al.
Science
. 2010 Jan;
327(5967):836-40.
PMID: 20044539
Meiotic recombination events cluster into narrow segments of the genome, defined as hotspots. Here, we demonstrate that a major player for hotspot specification is the Prdm9 gene. First, two mouse...
4.
Metzler-Guillemain C, de Massy B
Chromosoma
. 2000 Jun;
109(1-2):133-8.
PMID: 10855504
The SPO11/TOPVIA family includes proteins from archaebacteria and eukaryotes. The protein member from the archaebacterium Sulfulobus shibatae is the catalytic subunit of TopoVI DNA topoisomerase. In Saccharomyces cerevisiae, Schizosaccharomyces pombe,...
5.
Mezard C, Baudat F, Debrauwere H, de Massy B, Smith K, Soustelle C, et al.
J Soc Biol
. 2000 Jun;
193(1):23-7.
PMID: 10851552
Recent studies in Saccharomyces cerevisiae have provided new insights in our understanding of the molecular mechanisms of meiotic recombination. Meiosis-specific DNA double-strand breaks have been detected and have been shown...
6.
Gangloff S, de Massy B, Arthur L, Rothstein R, Fabre F
EMBO J
. 1999 Mar;
18(6):1701-11.
PMID: 10075939
Yeast cells mutant for TOP3, the gene encoding the evolutionary conserved type I-5' topoisomerase, display a wide range of phenotypes including altered cell cycle, hyper-recombination, abnormal gene expression, poor mating,...
7.
Dardalhon M, de Massy B, Nicolas A, Averbeck D
Curr Genet
. 1998 Jul;
34(1):30-42.
PMID: 9683673
Mitotic recombination within the ARG4 gene of Saccharomyces cerevisiae was analysed after treatment of cells with the recombinogenic agent 8-methoxypsoralen (8-MOP) plus UVA. The appearance of DNA double-strand breaks (DSBs)...
8.
Bergerat A, de Massy B, Gadelle D, Varoutas P, Nicolas A, Forterre P
Nature
. 1997 Mar;
386(6623):414-7.
PMID: 9121560
Type II topoisomerases help regulate DNA topology during transcription, replication and recombination by catalysing DNA strand transfer through transient double-stranded breaks. All type II topoisomerases described so far are members...
9.
de Massy B, Rocco V, Nicolas A
EMBO J
. 1995 Sep;
14(18):4589-98.
PMID: 7556102
Initiation of meiotic recombination in the yeast Saccharomyces cerevisiae occurs by localized DNA double-strand breaks (DSBs) at several locations in the genome, corresponding to hot spots for meiotic gene conversion...
10.
de Massy B, Baudat F, Nicolas A
Proc Natl Acad Sci U S A
. 1994 Dec;
91(25):11929-33.
PMID: 7991559
In most eukaryotes during prophase I of meiosis, homologous chromosomes pair and recombine by coordinated molecular and cellular processes. To directly test whether or not the early steps of the...