Ewa Sitnicka
Overview
Explore the profile of Ewa Sitnicka including associated specialties, affiliations and a list of published articles.
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38
Citations
1691
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Recent Articles
11.
Boiers C, Richardson S, Laycock E, Zriwil A, Turati V, Brown J, et al.
Dev Cell
. 2018 Jan;
44(3):362-377.e7.
PMID: 29290585
ETV6-RUNX1 is associated with childhood acute B-lymphoblastic leukemia (cALL) functioning as a first-hit mutation that initiates a clinically silent pre-leukemia in utero. Because lineage commitment hierarchies differ between embryo and...
12.
Moraghebi R, Kirkeby A, Chaves P, Ronn R, Sitnicka E, Parmar M, et al.
Stem Cell Res Ther
. 2017 Aug;
8(1):190.
PMID: 28841906
Background: Mesenchymal stromal cells (MSCs) are currently being evaluated in numerous pre-clinical and clinical cell-based therapy studies. Furthermore, there is an increasing interest in exploring alternative uses of these cells...
13.
Kristiansen T, Gyllenback E, Zriwil A, Bjorklund T, Daniel J, Sitnicka E, et al.
Immunity
. 2016 Aug;
45(2):346-57.
PMID: 27533015
Hematopoietic stem cells (HSCs) undergo a functional switch in neonatal mice hallmarked by a decrease in self-renewing divisions and entry into quiescence. Here, we investigated whether the developmental attenuation of...
14.
Zriwil A, Boiers C, Wittmann L, Green J, Woll P, Jacobsen S, et al.
Blood
. 2016 May;
128(2):217-26.
PMID: 27207794
Although it is well established that unique B-cell lineages develop through distinct regulatory mechanisms during embryonic development, much less is understood about the differences between embryonic and adult B-cell progenitor...
15.
Drissen R, Buza-Vidas N, Woll P, Thongjuea S, Gambardella A, Giustacchini A, et al.
Nat Immunol
. 2016 Apr;
17(6):666-676.
PMID: 27043410
According to current models of hematopoiesis, lymphoid-primed multi-potent progenitors (LMPPs) (Lin(-)Sca-1(+)c-Kit(+)CD34(+)Flt3(hi)) and common myeloid progenitors (CMPs) (Lin(-)Sca-1(+)c-Kit(+)CD34(+)CD41(hi)) establish an early branch point for separate lineage-commitment pathways from hematopoietic stem cells,...
16.
Renoux V, Zriwil A, Peitzsch C, Michaelsson J, Friberg D, Soneji S, et al.
Immunity
. 2015 Aug;
43(2):394-407.
PMID: 26287684
Natural killer (NK) cells are cytotoxic lymphocytes and play a vital role in controlling viral infections and cancer. In contrast to B and T lymphopoiesis where cellular and regulatory pathways...
17.
Cichocki F, Sitnicka E, Bryceson Y
Semin Immunol
. 2014 Mar;
26(2):114-26.
PMID: 24594002
Bone marrow-derived natural killer (NK) cells constitute the major subset of cytotoxic lymphocytes in peripheral blood. They provide innate defense against intracellular infection or malignancy and contribute to immune homeostasis....
18.
Boiers C, Carrelha J, Lutteropp M, Luc S, Green J, Azzoni E, et al.
Cell Stem Cell
. 2013 Sep;
13(5):535-48.
PMID: 24054998
In jawed vertebrates, development of an adaptive immune-system is essential for protection of the born organism against otherwise life-threatening pathogens. Myeloid cells of the innate immune system are formed early...
19.
Mead A, Kharazi S, Atkinson D, Macaulay I, Pecquet C, Loughran S, et al.
Cell Rep
. 2013 Jun;
3(6):1766-76.
PMID: 23727242
Whether signals mediated via growth factor receptors (GFRs) might influence lineage fate in multipotent progenitors (MPPs) is unclear. We explored this issue in a mouse knockin model of gain-of-function Flt3-ITD...
20.
Mansour A, Abou-Ezzi G, Sitnicka E, Jacobsen S, Wakkach A, Blin-Wakkach C
J Exp Med
. 2012 Feb;
209(3):537-49.
PMID: 22351931
Formation of the hematopoietic stem cell (HSC) niche in bone marrow (BM) is tightly associated with endochondral ossification, but little is known about the mechanisms involved. We used the oc/oc...