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Evita G van den Herik

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Articles 9
Citations 2408
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Recent Articles
1.
Debette S, Kamatani Y, Metso T, Kloss M, Chauhan G, Engelter S, et al.
Nat Genet . 2014 Nov; 47(1):78-83. PMID: 25420145
Cervical artery dissection (CeAD), a mural hematoma in a carotid or vertebral artery, is a major cause of ischemic stroke in young adults although relatively uncommon in the general population...
2.
Willer C, Schmidt E, Sengupta S, Peloso G, Gustafsson S, Kanoni S, et al.
Nat Genet . 2013 Oct; 45(11):1274-1283. PMID: 24097068
Levels of low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, triglycerides and total cholesterol are heritable, modifiable risk factors for coronary artery disease. To identify new loci and refine known...
3.
Do R, Willer C, Schmidt E, Sengupta S, Gao C, Peloso G, et al.
Nat Genet . 2013 Oct; 45(11):1345-52. PMID: 24097064
Triglycerides are transported in plasma by specific triglyceride-rich lipoproteins; in epidemiological studies, increased triglyceride levels correlate with higher risk for coronary artery disease (CAD). However, it is unclear whether this...
4.
Sonneveld M, van Dijk A, van den Herik E, Van Loon J, de Lau L, van der Lugt A, et al.
Atherosclerosis . 2013 Oct; 230(2):210-5. PMID: 24075746
Background: Large population studies have revealed that increased von Willebrand Factor (VWF) levels are associated with an increased risk of ischemic stroke. In previous studies VWF was associated with atherosclerosis...
5.
van den Herik E, de Lau L, Mohamad A, Ikram M, Koudstaal P
Int J Stroke . 2011 Oct; 7(3):219-23. PMID: 22011019
Background: Recent genomewide association studies have revealed an association between two single nucleotide polymorphisms, rs11833579 and rs12425791, and ischemic stroke. Aim: To gain more insight in pathophysiological mechanisms underlying the...
6.
van den Herik E, Cheung E, de Lau L, den Hertog H, Leebeek F, Dippel D, et al.
Thromb Haemost . 2010 Dec; 105(3):430-4. PMID: 21136017
Fibrinogen γ' (γ') is a natural isoform of fibrinogen, and alters the rate of formation and the properties of clots. It could therefore affect outcome after ischaemic stroke. The prognostic...
7.
den Hertog H, van den Herik E, Dippel D, Koudstaal P, de Maat M
Cerebrovasc Dis . 2010 Feb; 29(4):372-5. PMID: 20145391
Background And Purpose: Elevated levels of C-reactive protein (CRP) are found in up to three quarters of patients with acute ischemic stroke and are associated with poor outcome. We investigated...
8.
de Lau L, den Hertog H, van den Herik E, Koudstaal P
Expert Rev Neurother . 2009 Aug; 9(8):1159-70. PMID: 19673605
The prognosis of transient ischemic attacks (TIAs) is not as favorable as previously thought. Given a risk of stroke of approximately 10% in the first week following a TIA, urgent...
9.
Ikram M, Seshadri S, Bis J, Fornage M, DeStefano A, Aulchenko Y, et al.
N Engl J Med . 2009 Apr; 360(17):1718-28. PMID: 19369658
Background: The genes underlying the risk of stroke in the general population remain undetermined. Methods: We carried out an analysis of genomewide association data generated from four large cohorts composing...