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Evi Masschelein

Explore the profile of Evi Masschelein including associated specialties, affiliations and a list of published articles. Areas
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Articles 21
Citations 397
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Recent Articles
1.
Passini F, Bornstein B, Rubin S, Kuperman Y, Krief S, Masschelein E, et al.
Cell Metab . 2025 Feb; PMID: 39919739
Systemic metabolism ensures energy homeostasis through inter-organ crosstalk regulating thermogenic adipose tissue. Unlike the well-described inductive role of the sympathetic system, the inhibitory signal ensuring energy preservation remains poorly understood....
2.
Gorski T, Casartelli N, Fitzgerald G, Horstman A, Masschelein E, Essers K, et al.
Skelet Muscle . 2024 Dec; 14(1):32. PMID: 39696460
Background: Hip osteoarthritis patients display higher levels of fatty infiltration (FI) in the gluteus minimus (GM) compared to other hip muscles. We investigated specific histological factors such as fiber type...
3.
Soro-Arnaiz I, Fitzgerald G, Cherkaoui S, Zhang J, Gilardoni P, Ghosh A, et al.
Dev Cell . 2024 Aug; 59(21):2850-2865.e8. PMID: 39121856
Muscle stem cells (MuSCs) enable muscle growth and regeneration after exercise or injury, but how metabolism controls their regenerative potential is poorly understood. We describe that primary metabolic changes can...
4.
Lenardic A, Domenig S, Zvick J, Bundschuh N, Tarnowska-Sengul M, Furrer R, et al.
J Clin Invest . 2024 May; 134(12). PMID: 38713532
Satellite cells, the stem cells of skeletal muscle tissue, hold a remarkable regeneration capacity and therapeutic potential in regenerative medicine. However, low satellite cell yield from autologous or donor-derived muscles...
5.
Fitzgerald G, Turiel G, Gorski T, Soro-Arnaiz I, Zhang J, Casartelli N, et al.
Commun Biol . 2023 Jan; 6(1):111. PMID: 36707617
Fatty infiltration, the ectopic deposition of adipose tissue within skeletal muscle, is mediated via the adipogenic differentiation of fibro-adipogenic progenitors (FAPs). We used single-nuclei and single-cell RNA sequencing to characterize...
6.
Masschelein E, De Smet S, Denhaerynck K, Ceulemans L, Monbaliu D, de Geest S
PLoS One . 2022 Oct; 17(10):e0273497. PMID: 36288368
Background: Transplantoux's MVT exercise intervention prepares organ transplant recipients to cycle or hike up France's Mont Ventoux. We aimed to assess (i) MVT's effects on patient-reported outcomes (PROs) and (ii)...
7.
DHulst G, Masschelein E, De Bock K
Mol Metab . 2022 Oct; 66:101615. PMID: 36252815
Objective: Exercise enhances the sensitivity of mammalian target of rapamycin complex 1 (mTORC1) to amino acids, in particular leucine. How long this enhanced sensitivity lasts, and which mechanisms control enhanced...
8.
Fan Z, Turiel G, Ardicoglu R, Ghobrial M, Masschelein E, Kocijan T, et al.
Cell Metab . 2021 Aug; 33(9):1793-1807.e9. PMID: 34358431
Exercise is a powerful driver of physiological angiogenesis during adulthood, but the mechanisms of exercise-induced vascular expansion are poorly understood. We explored endothelial heterogeneity in skeletal muscle and identified two...
9.
Cappelle M, Masschelein E, Vos R, Van Remoortel H, Smets S, Vanbekbergen J, et al.
Transplant Proc . 2021 May; 53(6):1836-1845. PMID: 34049699
Background: Organ transplantation is a life-saving intervention that improves quality of life of patients with irreversible organ failure. Although exercise training immediately after transplantation has been suggested to be beneficial,...
10.
DHulst G, Masschelein E, De Bock K
Nutrients . 2021 Apr; 13(5). PMID: 33919313
Increased amino acid availability acutely stimulates protein synthesis partially via activation of mechanistic target of rapamycin complex 1 (mTORC1). Plant-and insect-based protein sources matched for total protein and/or leucine to...