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Evan S Forsythe

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Articles 16
Citations 245
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Recent Articles
1.
Bryant J, McCabe J, Klews C, Johnson M, Atchley A, Cousins T, et al.
Vet Sci . 2025 Jan; 12(1). PMID: 39852926
Inflammatory bowel disease (IBD) is increasing among mammals around the world, and domestic dogs are no exception. There is no approved cure for canine IBD with limited treatment options. Novel...
2.
Yang Y, Forsythe E, Ding Y, Zhang D, Bai W
Genome Biol Evol . 2023 Jul; 15(8). PMID: 37515592
The interaction between the nuclear and chloroplast genomes in plants is crucial for preserving essential cellular functions in the face of varying rates of mutation, levels of selection, and modes...
3.
Sloan D, Warren J, Williams A, Kuster S, Forsythe E
Genome Biol Evol . 2022 Dec; 15(1). PMID: 36583227
There is remarkable variation in the rate at which genetic incompatibilities in molecular interactions accumulate. In some cases, minor changes-even single-nucleotide substitutions-create major incompatibilities when hybridization forces new variants to...
4.
Grover C, Forsythe E, Sharbrough J, Miller E, Conover J, DeTar R, et al.
Genetics . 2022 Aug; 222(2). PMID: 35951749
Cytonuclear coevolution is a common feature among plants, which coordinates gene expression and protein products between the nucleus and organelles. Consequently, lineage-specific differences may result in incompatibilities between the nucleus...
5.
Forsythe E, Grover C, Miller E, Conover J, Arick 2nd M, Chavarro M, et al.
Proc Natl Acad Sci U S A . 2022 Jul; 119(30):e2204187119. PMID: 35858449
Mitochondrial and plastid functions depend on coordinated expression of proteins encoded by genomic compartments that have radical differences in copy number of organellar and nuclear genomes. In polyploids, doubling of...
6.
Rei Liao J, Friso G, Forsythe E, Michel E, Williams A, Boguraev S, et al.
J Biol Chem . 2022 Jan; 298(3):101609. PMID: 35065075
The chloroplast chaperone CLPC1 unfolds and delivers substrates to the stromal CLPPRT protease complex for degradation. We previously used an in vivo trapping approach to identify interactors with CLPC1 in...
7.
Williams A, Carter O, Forsythe E, Mendoza H, Sloan D
Mol Phylogenet Evol . 2022 Jan; 168:107395. PMID: 35033670
While the chloroplast (plastid) is known for its role in photosynthesis, it is also involved in many other metabolic pathways essential for plant survival. As such, plastids contain an extensive...
8.
Forsythe E, Williams A, Sloan D
Plant Cell . 2021 Mar; 33(4):980-997. PMID: 33764472
Nuclear and plastid (chloroplast) genomes experience different mutation rates, levels of selection, and transmission modes, yet key cellular functions depend on their coordinated interactions. Functionally related proteins often show correlated...
9.
Forsythe E, Nelson A, Beilstein M
Genome Biol Evol . 2020 Oct; 12(9):1646-1663. PMID: 33011798
Phylogenomic analyses are recovering previously hidden histories of hybridization, revealing the genomic consequences of these events on the architecture of extant genomes. We applied phylogenomic techniques and several complementary statistical...
10.
Dew-Budd K, Cheung J, Palos K, Forsythe E, Beilstein M
PLoS One . 2020 Apr; 15(4):e0222687. PMID: 32271752
The telomerase ribonucleoprotein complex (RNP) is essential for genome stability and performs this role through the addition of repetitive DNA to the ends of chromosomes. The telomerase enzyme is composed...