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Evan D Brutinel

Explore the profile of Evan D Brutinel including associated specialties, affiliations and a list of published articles. Areas
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Articles 21
Citations 636
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Recent Articles
11.
Brutinel E, Gralnick J
Appl Microbiol Biotechnol . 2011 Nov; 93(1):41-8. PMID: 22072194
The genus Shewanella contains Gram negative γ-proteobacteria capable of reducing a wide range of substrates, including insoluble metals and carbon electrodes. The utilization of insoluble respiratory substrates by bacteria requires...
12.
Fuchs E, Brutinel E, Jones A, Fulcher N, Urbanowski M, Yahr T, et al.
J Bacteriol . 2010 May; 192(14):3553-64. PMID: 20494996
Vfr is a global regulator of virulence factor expression in the human pathogen Pseudomonas aeruginosa. Although indirect evidence suggests that Vfr activity is controlled by cyclic AMP (cAMP), it has...
13.
Vakulskas C, Brutinel E, Yahr T
J Bacteriol . 2010 May; 192(14):3597-607. PMID: 20453093
ExsA is a member of the AraC family of transcriptional activators and is required for expression of the Pseudomonas aeruginosa type III secretion system (T3SS). ExsA-dependent promoters consist of two...
14.
Fuchs E, Brutinel E, Klem E, Fehr A, Yahr T, Wolfgang M
J Bacteriol . 2010 Mar; 192(11):2779-90. PMID: 20348254
Cyclic AMP (cAMP) is an important second messenger signaling molecule that controls a wide variety of eukaryotic and prokaryotic responses to extracellular cues. For cAMP-dependent signaling pathways to be effective,...
15.
Brutinel E, Vakulskas C, Yahr T
J Bacteriol . 2009 Dec; 192(6):1479-86. PMID: 20008065
Pseudomonas aeruginosa utilizes a type III secretion system (T3SS) to damage eukaryotic host cells and evade phagocytosis. Transcription of the T3SS regulon is controlled by ExsA, a member of the...
16.
Brutinel E, Vakulskas C, Yahr T
J Bacteriol . 2009 Apr; 191(12):3811-21. PMID: 19376850
The opportunistic pathogen Pseudomonas aeruginosa utilizes a type III secretion system (T3SS) to evade phagocytosis and damage eukaryotic cells. Transcription of the T3SS regulon is controlled by ExsA, a member...
17.
Brutinel E, Yahr T
Curr Opin Microbiol . 2008 Apr; 11(2):128-33. PMID: 18396449
The bacterial flagellum and the highly related injectisome (or needle complex) are among the most complicated multi-protein structures found in Gram-negative microorganisms. The assembly of both structures is dependent upon...
18.
Brutinel E, Vakulskas C, Brady K, Yahr T
Mol Microbiol . 2008 Apr; 68(3):657-71. PMID: 18373522
Expression of the Pseudomonas aeruginosa type III secretion system (T3SS) is activated by ExsA, a member of the AraC/XylS family of transcriptional regulators. In the present study we examine the...
19.
Urbanowski M, Brutinel E, Yahr T
Infect Immun . 2007 Jul; 75(9):4432-9. PMID: 17635873
Transcription of the Pseudomonas aeruginosa type III secretion system (T3SS) is induced under Ca(2+)-limiting growth conditions or following the contact of the bacteria with host cells. The regulatory response to...
20.
Zheng Z, Chen G, Joshi S, Brutinel E, Yahr T, Chen L
J Biol Chem . 2007 Jan; 282(9):6136-42. PMID: 17197437
Many Gram-negative pathogens utilize type III secretion systems (T3SS) to translocate effector proteins into eukaryotic host cells. Expression of T3SS genes is highly regulated and is often coupled to type...