Evan A Farkash
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Explore the profile of Evan A Farkash including associated specialties, affiliations and a list of published articles.
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43
Citations
772
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Recent Articles
1.
McCann M, Fry C, Maile M, Farkash E, Cummings B, Flott T, et al.
Am J Respir Cell Mol Biol
. 2025 Feb;
PMID: 39918954
Organ-specific metabolic pathways, including those related to mitochondrial metabolism, could provide insight to mechanisms underlying sepsis-induced organ dysfunction. However, it remains unclear if metabolic changes result from or precede clinical...
2.
Blades C, Dumanian Z, Wang Y, Wang Z, Li B, Washington K, et al.
Front Transplant
. 2024 Dec;
3:1504959.
PMID: 39712036
Introduction: As research advances in vascularized composite allotransplantation (VCA), large animal models are essential for translational studies related to immune rejection and graft survival. However, procurement of large flaps can...
3.
Diebold M, Farkash E, Barnes J, Regele H, Kozakowski N, Schatzl M, et al.
Transpl Int
. 2024 Jul;
37:13209.
PMID: 38979120
Transcript analyses highlight an important contribution of natural killer (NK) cells to microvascular inflammation (MVI) in antibody-mediated rejection (ABMR), but only few immunohistologic studies have quantified their spatial distribution within...
4.
Scavuzzi B, van Drongelen V, Kaur B, Fox J, Liu J, Mesquita-Ferrari R, et al.
Commun Biol
. 2022 Jul;
5(1):751.
PMID: 35902632
The HLA-DRB1*03:01 allele is a major genetic risk factor in systemic lupus erythematosus (SLE), but the mechanistic basis of the association is unclear. Here we show that in the presence...
5.
Menon R, Otto E, Berthier C, Nair V, Farkash E, Hodgin J, et al.
Kidney Int
. 2021 Dec;
101(4):779-792.
PMID: 34952098
Increased podocyte detachment begins immediately after kidney transplantation and is associated with long-term allograft failure. We hypothesized that cell-specific transcriptional changes in podocytes and glomerular endothelial cells after transplantation would...
6.
Rosales I, Yang C, Farkash E, Ashry T, Ge J, Aljabban I, et al.
Am J Transplant
. 2021 Nov;
22(3):705-716.
PMID: 34726836
Intragraft events thought to be relevant to the development of tolerance are here subjected to a comprehensive mechanistic study during long-term spontaneous tolerance that occurs in C57BL/6 mice that receive...
7.
de Mattos Barbosa M, Lefferts A, Huynh D, Liu H, Zhang Y, Fu B, et al.
JCI Insight
. 2021 Jul;
6(17).
PMID: 34283811
Host genes define the severity of inflammation and immunity but specific loci doing so are unknown. Here we show that TNF receptor superfamily member 13B (TNFRSF13B) variants, which enhance defense...
8.
Shi H, Gandhi A, Smith S, Wang Q, Chiang D, Yalavarthi S, et al.
JCI Insight
. 2021 Jul;
6(17).
PMID: 34264868
Neutrophil-mediated activation and injury of the endothelium play roles in the pathogenesis of diverse disease states ranging from autoimmunity to cancer to COVID-19. Neutralization of cationic proteins (such as neutrophil...
9.
Clark K, McMurry K, Naik A, Parasuraman R, Court C, Colquhoun D, et al.
Exp Clin Transplant
. 2021 Jun;
20(3):306-310.
PMID: 34085917
Rabbit antithymocyte globulin is a lymphocytedepleting agent commonly used as induction therapy in kidney transplants. Although its use is generally safe and well tolerated, serious side effects can occur. Here,...
10.
Shi H, Gandhi A, Smith S, Wang Q, Chiang D, Yalavarthi S, et al.
medRxiv
. 2021 Mar;
PMID: 33655266
Neutrophil-mediated activation and injury of the endothelium play a role in the pathogenesis of diverse disease states ranging from autoimmunity to cancer to COVID-19. Neutralization of cationic proteins (such as...