Eva S Werstiuk
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Explore the profile of Eva S Werstiuk including associated specialties, affiliations and a list of published articles.
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12
Citations
194
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Recent Articles
1.
Guanosine stimulates neurite outgrowth in PC12 cells via activation of heme oxygenase and cyclic GMP
Bau C, Middlemiss P, Hindley S, Jiang S, Ciccarelli R, Caciagli F, et al.
Purinergic Signal
. 2008 Apr;
1(2):161-72.
PMID: 18404501
Undifferentiated rat pheochromocytoma (PC12) cells extend neurites when cultured in the presence of nerve growth factor (NGF). Extracellular guanosine synergistically enhances NGF-dependent neurite outgrowth. We investigated the mechanism by which...
2.
Jiang S, Zavitz C, Wang J, Saraf A, Zielinski R, Ramsbottom J, et al.
Purinergic Signal
. 2008 Apr;
2(4):651-61.
PMID: 18404468
Wound healing is a complex sequence of cellular and molecular processes that involves multiple cell types and biochemical mediators. Several growth factors have been identified that regulate tissue repair, including...
3.
Pettifer K, Jiang S, Bau C, Ballerini P, DAlimonte I, Werstiuk E, et al.
Purinergic Signal
. 2008 Apr;
3(4):399-409.
PMID: 18404453
Guanosine exerts neuroprotective effects in the central nervous system. Apoptosis, a morphological form of programmed cell death, is implicated in the pathophysiology of Parkinson's disease (PD). MPP(+), a dopaminergic neurotoxin,...
4.
Jawed S, Kim B, Ottenhof T, Brown G, Werstiuk E, Niles L
Eur J Pharmacol
. 2007 Feb;
560(1):17-22.
PMID: 17303109
We have reported that valproic acid upregulates melatonin MT1 receptor expression in rat C6 glioma cells. In addition to its anticonvulsant and mood stabilizing properties, valproic acid can also inhibit...
5.
Jiang S, Khan M, Lu Y, Werstiuk E, Rathbone M
Exp Brain Res
. 2004 Dec;
162(1):56-62.
PMID: 15599730
Enteric glia share morphological, biochemical, and functional properties with astrocytes. Thus, like astrocytes, transplantation of enteric glia into the central nervous system (CNS) might facilitate the development of the characteristics...
6.
Di Iorio P, Ballerini P, Traversa U, Nicoletti F, DAlimonte I, Kleywegt S, et al.
Glia
. 2004 Apr;
46(4):356-68.
PMID: 15095366
Guanosine has many trophic effects in the CNS, including the stimulation of neurotrophic factor synthesis and release by astrocytes, which protect neurons against excitotoxic death. Therefore, we questioned whether guanosine...
7.
Pettifer K, Kleywegt S, Bau C, Ramsbottom J, Vertes E, Ciccarelli R, et al.
Neuroreport
. 2004 Apr;
15(5):833-6.
PMID: 15073525
Apoptosis is implicated in the pathophysiology of Alzheimer's disease. Extracellular guanosine inhibits staurosporine-induced apoptosis in astrocytes. We examined whether guanosine protects SH-SY5Y human neuroblastoma cells against beta-amyloid(betaA)-induced apoptosis. Addition of...
8.
Jiang S, Khan M, Lu Y, Wang J, Buttigieg J, Werstiuk E, et al.
Neuroreport
. 2003 Dec;
14(18):2463-7.
PMID: 14663211
Functional loss after spinal cord injury (SCI) is caused, in part, by demyelination of axons surviving the trauma. Administration of guanosine (8 mg/kg/day, i.p.) for 7 consecutive days, starting 5...
9.
Jiang S, Khan M, Wang J, Middlemiss P, Werstiuk E, Wickson R, et al.
Neuroreport
. 2003 Jul;
14(10):1301-4.
PMID: 12876461
Transected dorsal root axons of adult rats can be induced to regenerate through the normally non-permissive environment of the dorsal root entry zone (DREZ) into the spinal cord by implanting...
10.
Jiang S, Wang J, Khan M, Middlemiss P, Salgado-Ceballos H, Werstiuk E, et al.
Exp Neurol
. 2003 Apr;
181(1):79-83.
PMID: 12710936
After spinal cord injury axonal regeneration is poor, but may be enhanced by the implantation of olfactory ensheathing glia (OEG). Enteric glia (EG) share many properties of OEG. Transected dorsal...