Eva Hug
Overview
Explore the profile of Eva Hug including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
13
Citations
451
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Pecquet C, Papadopoulos N, Balligand T, Chachoua I, Tisserand A, Vertenoeil G, et al.
Blood
. 2022 Nov;
141(8):917-929.
PMID: 36356299
Mutant calreticulin (CALR) proteins resulting from a -1/+2 frameshifting mutation of the CALR exon 9 carry a novel C-terminal amino acid sequence and drive the development of myeloproliferative neoplasms (MPNs)....
2.
Achyutuni S, Nivarthi H, Majoros A, Hug E, Schueller C, Jia R, et al.
Am J Hematol
. 2021 Mar;
96(6):698-707.
PMID: 33761144
Myeloproliferative neoplasms (MPNs) are characterized by a pathologic expansion of myeloid lineages. Mutations in JAK2, CALR and MPL genes are known to be three prominent MPN disease drivers. Mutant CALR...
3.
Balligand T, Achouri Y, Pecquet C, Gaudray G, Colau D, Hug E, et al.
Leukemia
. 2019 Sep;
34(2):510-521.
PMID: 31471561
Frameshifting mutations (-1/+2) of the calreticulin (CALR) gene are responsible for the development of essential thrombocythemia (ET) and primary myelofibrosis (PMF). The mutant CALR proteins activate the thrombopoietin receptor (TpoR)...
4.
Schischlik F, Jager R, Rosebrock F, Hug E, Schuster M, Holly R, et al.
Blood
. 2019 May;
134(2):199-210.
PMID: 31064751
Ph-negative myeloproliferative neoplasms (MPNs) are hematological cancers that can be subdivided into entities with distinct clinical features. Somatic mutations in , , and have been described as drivers of the...
5.
Pecquet C, Chachoua I, Roy A, Balligand T, Vertenoeil G, Leroy E, et al.
Blood
. 2019 Mar;
133(25):2669-2681.
PMID: 30902807
Calreticulin (CALR) +1 frameshift mutations in exon 9 are prevalent in myeloproliferative neoplasms. Mutant CALRs possess a new C-terminal sequence rich in positively charged amino acids, leading to activation of...
6.
Setz C, Hug E, Khadour A, Abdelrasoul H, Bilal M, Hobeika E, et al.
Cell Rep
. 2018 Jul;
24(2):391-405.
PMID: 29996100
Activation of phosphoinositide 3-kinase (PI3K) signaling plays a central role in regulating proliferation and survival of B cells. Here, we tested the hypothesis that B cell receptor (BCR)-mediated activation of...
7.
Ubelhart R, Hug E, Bach M, Wossning T, Minden M, Horn A, et al.
Nat Immunol
. 2015 Jun;
16(7):785.
PMID: 26086144
No abstract available.
8.
Ubelhart R, Hug E, Bach M, Wossning T, Minden M, Horn A, et al.
Nat Immunol
. 2015 Apr;
16(5):534-43.
PMID: 25848865
Mature B cells express immunoglobulin M (IgM)- and IgD-isotype B cell antigen receptors, but the importance of IgD for B cell function has been unclear. By using a cellular in...
9.
Iacovelli S, Hug E, Bennardo S, Duehren-von Minden M, Gobessi S, Rinaldi A, et al.
Blood
. 2015 Jan;
125(10):1578-88.
PMID: 25564405
Chronic lymphocytic leukemia (CLL) is a common B-cell malignancy characterized by a highly variable course and outcome. The disease is believed to be driven by B-cell receptor (BCR) signals generated...
10.
Bach M, Hug E, Werner M, Holch J, Sprissler C, Pechloff K, et al.
J Immunol
. 2013 Dec;
192(3):1024-33.
PMID: 24376268
The development of hematopoietic neoplasms is often associated with mutations, altered gene expression or chromosomal translocations. Recently, the t(5, 9)(q33;q22) translocation was found in a subset of peripheral T cell...