Eunju Im
Overview
Explore the profile of Eunju Im including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
18
Citations
564
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Im E, Jiang Y, Stavrides P, Darji S, Erdjument-Bromage H, Neubert T, et al.
Sci Adv
. 2023 Jul;
9(30):eadg1925.
PMID: 37494443
Lysosome dysfunction arises early and propels Alzheimer's disease (AD). Herein, we show that amyloid precursor protein (APP), linked to early-onset AD in Down syndrome (DS), acts directly via its β-C-terminal...
2.
Kim M, Im E, Jin Ahn Y
Iran J Biotechnol
. 2022 Nov;
20(3):e3177.
PMID: 36381282
Background: In () culture, acetate accumulates as an undesirable by-product of aerobic fermentation on glucose and inhibits cell growth and recombinant protein production. Objectives: We examined whether the heterologous expression...
3.
Bendl J, Hauberg M, Girdhar K, Im E, Vicari J, Rahman S, et al.
Nat Neurosci
. 2022 Sep;
25(10):1366-1378.
PMID: 36171428
To characterize the dysregulation of chromatin accessibility in Alzheimer's disease (AD), we generated 636 ATAC-seq libraries from neuronal and nonneuronal nuclei isolated from the superior temporal gyrus and entorhinal cortex...
4.
Lee J, Yang D, Goulbourne C, Im E, Stavrides P, Pensalfini A, et al.
Nat Neurosci
. 2022 Jun;
25(6):688-701.
PMID: 35654956
Autophagy is markedly impaired in Alzheimer's disease (AD). Here we reveal unique autophagy dysregulation within neurons in five AD mouse models in vivo and identify its basis using a neuron-specific...
5.
Lee Y, Im E, Hyun M, Park J, Chung K
J Biol Chem
. 2020 Dec;
296:100245.
PMID: 33380426
Down syndrome (DS) is mainly caused by an extra copy of chromosome 21 (trisomy 21), and patients display a variety of developmental symptoms, including characteristic facial features, physical growth delay,...
6.
Lee Y, Im E, Kim H, Lew B, Sim W, Lee J, et al.
Metabolites
. 2020 Apr;
10(4).
PMID: 32235609
Male pattern baldness (MPB) has been associated with dihydrotestosterone (DHT) expression. Finasteride treats MPB by inhibiting 5-alpha reductase and blocking DHT production. In this study, we aimed to identify metabolic...
7.
Jiang Y, Sato Y, Im E, Berg M, Bordi M, Darji S, et al.
J Neurosci
. 2019 May;
39(27):5255-5268.
PMID: 31043483
Lysosomal failure underlies pathogenesis of numerous congenital neurodegenerative disorders and is an early and progressive feature of Alzheimer's disease (AD) pathogenesis. Here, we report that lysosomal dysfunction in Down ayndrome...
8.
Im E, Lew B, Lee M, Lee J, Paeng K, Chung B
J Chromatogr B Analyt Technol Biomed Life Sci
. 2019 Feb;
1109:45-53.
PMID: 30716600
A simultaneous quantitative profiling method for androgens and prostaglandins using ultra-high-performance liquid chromatography-tandem mass spectrometry was developed and validated to evaluate urinary androgen and prostaglandin levels. Solid-phase extraction and liquid-liquid...
9.
Lee J, Rao M, Yang D, Stavrides P, Im E, Pensalfini A, et al.
Autophagy
. 2018 Oct;
15(3):543-557.
PMID: 30269645
Autophagy-lysosome pathway (ALP) disruption is considered pathogenic in multiple neurodegenerative diseases; however, current methods are inadequate to investigate macroautophagy/autophagy flux in brain in vivo and its therapeutic modulation. Here, we...
10.
Im E, Yoon J, Lee H, Chung K
J Cell Physiol
. 2016 Sep;
232(8):2083-2093.
PMID: 27648923
Human telomerase reverse transcriptase (hTERT) is the catalytic subunit of telomerase, an RNA-dependent DNA polymerase that elongates telomeric DNA. hTERT displays several extra-telomeric functions that are independent of its telomere-regulatory...