Eugene P Kennedy
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Explore the profile of Eugene P Kennedy including associated specialties, affiliations and a list of published articles.
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51
Citations
1304
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Recent Articles
1.
Hoffe S, Aguilera T, Parikh P, Ghaly M, Herman J, Caster J, et al.
Future Oncol
. 2024 Jan;
20(8):437-446.
PMID: 38264869
Ablative doses of stereotactic body radiotherapy (SBRT) may improve pancreatic cancer outcomes but may carry greater potential for gastrointestinal toxicity. Rucosopasem, an investigational selective dismutase mimetic that converts superoxide to...
2.
Mapuskar K, Pulliam C, Tomanek-Chalkley A, Rastogi P, Wen H, Dayal S, et al.
Redox Biol
. 2024 Jan;
70:103022.
PMID: 38215546
Purpose: Cisplatin contributes to acute kidney injury (AKI) and chronic kidney disease (CKD) that occurs with greater frequency and severity in older patients. Age-associated cisplatin sensitivity in human fibroblasts involves...
3.
Johnson T, MacDonald T, Pacholczyk R, Aguilera D, Al-Basheer A, Bajaj M, et al.
Neuro Oncol
. 2023 Sep;
26(2):348-361.
PMID: 37715730
Background: Recurrent brain tumors are the leading cause of cancer death in children. Indoleamine 2,3-dioxygenase (IDO) is a targetable metabolic checkpoint that, in preclinical models, inhibits anti-tumor immunity following chemotherapy....
4.
Beatty G, Delman D, Yu J, Liu M, Li J, Zhang L, et al.
Clin Cancer Res
. 2023 Aug;
29(17):3514-3525.
PMID: 37534996
Purpose: Determinants of treatment outcomes to chemotherapy-based regimens in metastatic pancreatic ductal adenocarcinoma (PDA) remain ill-defined. Our aim was to examine tissue-based correlates of treatment response and resistance using matched...
5.
Zakharia Y, McWilliams R, Rixe O, Drabick J, Shaheen M, Grossmann K, et al.
J Immunother Cancer
. 2021 Jun;
9(6).
PMID: 34117113
Background: The indoleamine 2,3-dioxygenase (IDO) pathway is a key counter-regulatory mechanism that, in cancer, is exploited by tumors to evade antitumor immunity. Indoximod is a small-molecule IDO pathway inhibitor that...
6.
Burrell S, Yeo T, Smeltzer S, Leiby B, Lavu H, Kennedy E, et al.
Oncol Nurs Forum
. 2018 Jun;
45(4):E53-E66.
PMID: 29947350
Objectives: To explore the relationship between 16 symptom clusters (SCs), clinical and demographic influencing factors, and clinical outcomes over time in patients with pancreatic cancer (PC) undergoing surgical resection. Sample...
7.
Burrell S, Yeo T, Smeltzer S, Leiby B, Lavu H, Kennedy E, et al.
Oncol Nurs Forum
. 2018 Jun;
45(4):E36-E52.
PMID: 29947349
Objectives: To describe patient-reported symptoms and symptom clusters in patients with pancreatic cancer (PC) undergoing surgical resection. Sample & Setting: 143 patients with stage II PC undergoing surgical resection alone...
8.
Vacchelli E, Aranda F, Eggermont A, Sautes-Fridman C, Tartour E, Kennedy E, et al.
Oncoimmunology
. 2015 May;
3(10):e957994.
PMID: 25941578
Indoleamine 2,3-dioxigenase 1 (IDO1) is the main enzyme that catalyzes the first, rate-limiting step of the so-called "kynurenine pathway", i.e., the metabolic cascade that converts the essential amino acid -tryptophan...
9.
Lavu H, Lengel H, Sell N, Baiocco J, Kennedy E, Yeo T, et al.
J Am Coll Surg
. 2015 Feb;
220(4):497-508.
PMID: 25667135
Background: Ethanol celiac plexus neurolysis (ECPN) has been shown to be effective in reducing cancer-related pain in patients with locally advanced pancreatic and periampullary adenocarcinoma (PPA). This study examined its...
10.
Mura Assifi M, Nguyen P, Agrawal N, Dedania N, Kennedy E, Sauter P, et al.
J Gastrointest Surg
. 2014 Jan;
18(3):523-31.
PMID: 24449000
Objectives: With the increased use of cross-sectional radiologic imaging in recent years, cystic lesions of the pancreas are being diagnosed with greater frequency. While pseuodocysts have historically accounted for the...