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Eugene Guorong Yang

Explore the profile of Eugene Guorong Yang including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Yang E, Mustafa N, Tan E, Poulsen A, Ramanujulu P, Chng W, et al.
J Med Chem . 2016 Aug; 59(18):8233-62. PMID: 27541357
Blockage of more than one oncoprotein or pathway is now a standard approach in modern cancer therapy. Multiple inhibition is typically achieved with two or more drugs. Herein, we describe...
2.
Nguyen T, Chua J, Seah K, Koo S, Yee J, Yang E, et al.
Sci Rep . 2016 Jan; 6:18658. PMID: 26791325
Contemporary chemotherapeutic treatments incorporate the use of several agents in combination. However, selecting the most appropriate drugs for such therapy is not necessarily an easy or straightforward task. Here, we...
3.
Lim K, Ong T, Tan Y, Yang E, Ren B, Seah K, et al.
Sci Rep . 2015 Sep; 5:14064. PMID: 26369364
Eukaryotic genomes are packed into discrete units, referred to as nucleosomes, by organizing around scaffolding histone proteins. The interplay between these histones and the DNA can dynamically regulate the function...
4.
Dymock B, Yang E, Chu-Farseeva Y, Yao L
Future Med Chem . 2014 Oct; 6(12):1439-71. PMID: 25329199
Consisting of four members, JAK1, JAK2, JAK3 and TYK2, the JAK kinases have emerged as important targets for proliferative and immune-inflammatory disorders. Recent progress in the discovery of selective inhibitors...