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Esperanza Arias

Explore the profile of Esperanza Arias including associated specialties, affiliations and a list of published articles. Areas
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Articles 29
Citations 6069
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Recent Articles
1.
Zapateria B, Arias E
Front Mol Biosci . 2025 Feb; 11:1516789. PMID: 39935707
Aging and cancer are intricately linked through shared molecular processes that influence both the onset of malignancy and the progression of age-related decline. As organisms age, cellular stress, genomic instability,...
2.
Khawaja R, Martin-Segura A, Santiago-Fernandez O, Sereda R, Lindenau K, McCabe M, et al.
Nat Aging . 2025 Feb; PMID: 39910244
Aging leads to progressive decline in organ and tissue integrity and function, partly due to loss of proteostasis and autophagy malfunctioning. A decrease with age in chaperone-mediated autophagy (CMA), a...
3.
Patel K, Arias E
Stem Cell Investig . 2023 Feb; 10:1. PMID: 36742282
No abstract available.
4.
Gomez-Sintes R, Arias E
Mol Aspects Med . 2021 Oct; 82:101025. PMID: 34629183
Chaperone-mediated autophagy (CMA) is a proteolytic process whereby selected intracellular proteins are degraded inside lysosomes. Owing to its selectivity, CMA participates in the modulation of specific regulatory proteins, thereby playing...
5.
Kaushik S, Tasset I, Arias E, Pampliega O, Wong E, Martinez-Vicente M, et al.
Ageing Res Rev . 2021 Sep; 72:101468. PMID: 34563704
Autophagy, an essential cellular process that mediates degradation of proteins and organelles in lysosomes, has been tightly linked to cellular quality control for its role as part of the proteostasis...
6.
Linares J, Zhang X, Martinez-Ordonez A, Duran A, Kinoshita H, Kasashima H, et al.
Mol Cell . 2021 Sep; 81(21):4509-4526.e10. PMID: 34560002
The interferon (IFN) pathway is critical for cytotoxic T cell activation, which is central to tumor immunosurveillance and successful immunotherapy. We demonstrate here that PKCλ/ι inactivation results in the hyper-stimulation...
7.
Klionsky D, Abdel-Aziz A, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, et al.
Autophagy . 2021 Feb; 17(1):1-382. PMID: 33634751
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our...
8.
Kudo Y, Sugimoto M, Arias E, Kasashima H, Cordes T, Linares J, et al.
Cancer Cell . 2020 Jun; 38(2):247-262.e11. PMID: 32589943
Oxidative stress plays a critical role in liver tissue damage and in hepatocellular carcinoma (HCC) initiation and progression. However, the mechanisms that regulate autophagy and metabolic reprogramming during reactive oxygen...
9.
Arias E, Cuervo A
Trends Endocrinol Metab . 2019 Nov; 31(1):53-66. PMID: 31699565
Autophagy contributes to cellular quality control and energetics through lysosomal breakdown and recycling of essential cellular components. Chaperone-mediated autophagy (CMA) adds to these autophagic functions the ability to timely and...
10.
Walters R, Arias E, Diaz A, Burgos E, Guan F, Tiano S, et al.
Cell Rep . 2018 Oct; 25(3):663-676.e6. PMID: 30332646
A hallmark of aging is a decline in metabolic homeostasis, which is attenuated by dietary restriction (DR). However, the interaction of aging and DR with the metabolome is not well...