Erwin G Van Meir
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Explore the profile of Erwin G Van Meir including associated specialties, affiliations and a list of published articles.
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Articles
133
Citations
13651
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Recent Articles
1.
Parag R, Yamamoto T, Saito K, Zhu D, Yang L, Van Meir E
Mol Neurobiol
. 2024 Jun;
62(1):900-917.
PMID: 38941066
Brain-specific angiogenesis inhibitor 1 (BAI1) belongs to the adhesion G-protein-coupled receptors, which exhibit large multi-domain extracellular N termini that mediate cell-cell and cell-matrix interactions. To explore the existence of BAI1...
2.
Kuranaga Y, Yu B, Osuka S, Zhang H, Devi N, Bae S, et al.
Cells
. 2024 May;
13(9.
PMID: 38727288
Glioblastoma (GBM) is a devastating brain cancer for which new effective therapies are urgently needed. GBM, after an initial response to current treatment regimens, develops therapeutic resistance, leading to rapid...
3.
Malta T, Sabedot T, Morosini N, Datta I, Garofano L, Vallentgoed W, et al.
Cancer Res
. 2023 Dec;
84(5):741-756.
PMID: 38117484
Significance: Standard treatments are related to loss of DNA methylation in IDHmut glioma, resulting in epigenetic activation of genes associated with tumor progression and alterations in the microenvironment that resemble...
4.
Shiu F, Wong J, Bhattacharya D, Kuranaga Y, Parag R, Alsharif H, et al.
Basic Clin Pharmacol Toxicol
. 2023 Jun;
133(4):353-363.
PMID: 37337931
Brain-specific angiogenesis inhibitor 3 (ADGRB3/BAI3) belongs to the family of adhesion G protein-coupled receptors. It is most highly expressed in the brain where it plays a role in synaptogenesis and...
5.
Hendrikse L, Haldipur P, Saulnier O, Millman J, Sjoboen A, Erickson A, et al.
Nature
. 2022 Nov;
612(7940):E12.
PMID: 36446943
No abstract available.
6.
Hendrikse L, Haldipur P, Saulnier O, Millman J, Sjoboen A, Erickson A, et al.
Nature
. 2022 Sep;
609(7929):1021-1028.
PMID: 36131014
Medulloblastoma (MB) comprises a group of heterogeneous paediatric embryonal neoplasms of the hindbrain with strong links to early development of the hindbrain. Mutations that activate Sonic hedgehog signalling lead to...
7.
Varn F, Johnson K, Martinek J, Huse J, Nasrallah M, Wesseling P, et al.
Cell
. 2022 Jun;
185(12):2184-2199.e16.
PMID: 35649412
The factors driving therapy resistance in diffuse glioma remain poorly understood. To identify treatment-associated cellular and genetic changes, we analyzed RNA and/or DNA sequencing data from the temporally separated tumor...
8.
Shiu F, Wong J, Yamamoto T, Lala T, Purcell R, Owino S, et al.
Exp Neurol
. 2022 Feb;
351:113994.
PMID: 35114205
The adhesion G protein-coupled receptor BAI1/ADGRB1 plays an important role in suppressing angiogenesis, mediating phagocytosis, and acting as a brain tumor suppressor. BAI1 is also a critical regulator of dendritic...
9.
Coltin H, Sundaresan L, Smith K, Skowron P, Massimi L, Eberhart C, et al.
Acta Neuropathol
. 2021 Aug;
142(5):859-871.
PMID: 34409497
Medulloblastoma, a common pediatric malignant central nervous system tumour, represent a small proportion of brain tumours in adults. Previously it has been shown that in adults, Sonic Hedgehog (SHH)-activated tumours...
10.
Snyder J, Huang R, Bai H, Rao V, Cornes S, Barnholtz-Sloan J, et al.
Neurooncol Adv
. 2021 Aug;
3(1):vdab088.
PMID: 34409295
Background: Although IDH-mutant tumors aggregate to the frontotemporal regions, the clustering pattern of IDH-wildtype tumors is less clear. As voxel-based lesion-symptom mapping (VLSM) has several limitations for solid lesion mapping,...