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Erin C Macaulay

Explore the profile of Erin C Macaulay including associated specialties, affiliations and a list of published articles. Areas
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Articles 20
Citations 140
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Recent Articles
1.
Keighley L, Lynch-Sutherland C, McDougall L, Almomani S, Stockwell P, Eccles M, et al.
Placenta . 2024 Sep; 158:10-13. PMID: 39312864
Transposable elements (TEs) play a crucial role in placental development and dysfunction. Our study examined TE expression in pre-eclampsia (PE) using RNA-seq datasets. We identified differentially expressed TEs and explored...
2.
Powell R, Moravec J, Jones G, Bhat B, Lin S, Planer J, et al.
Am J Respir Cell Mol Biol . 2023 Dec; 70(1):81-84. PMID: 38156802
No abstract available.
3.
Keighley L, Lynch-Sutherland C, Almomani S, Eccles M, Macaulay E
Placenta . 2023 Jun; 141:57-64. PMID: 37301654
The human placenta is a vital connection between maternal and fetal tissues, allowing for the exchange of molecules and modulation of immune interactions during pregnancy. Interestingly, some of the placenta's...
4.
Lynch-Sutherland C, McDougall L, Stockwell P, Almomani S, Weeks R, Ludgate J, et al.
Mol Genet Genomics . 2023 Jun; 298(5):1045-1058. PMID: 37269361
Transposable elements (TEs) are genetic elements that have evolved as crucial regulators of human development and cancer, functioning as both genes and regulatory elements. When TEs become dysregulated in cancer...
5.
Powell R, Pattison S, Moravec J, Bhat B, Guirguis N, Markie D, et al.
Cold Spring Harb Mol Case Stud . 2022 Apr; 8(3). PMID: 35483879
Tuberous sclerosis complex (TSC) is an inheritable disorder characterized by the formation of benign yet disorganized tumors in multiple organ systems. Germline mutations in the (hamartin) or more frequently (tuberin)...
6.
Hossain S, Lynch-Sutherland C, Chatterjee A, Macaulay E, Eccles M
Epigenomes . 2021 Dec; 5(3). PMID: 34968365
Cancer is the second leading cause of mortality and morbidity in the developed world. Cancer progression involves genetic and epigenetic alterations, accompanied by aggressive changes, such as increased immune evasion,...
7.
Stockwell P, Lynch-Sutherland C, Chatterjee A, Macaulay E, Eccles M
Curr Protoc . 2021 Aug; 1(8):e206. PMID: 34387946
Transposable elements (TEs) are key regulators of both development and disease; however, their repetitive nature presents substantial computational challenges to their analysis. Due to a lack of computational tools and...
8.
Almomani S, Alsaleh A, Weeks R, Chatterjee A, Day R, Honda I, et al.
Placenta . 2021 Jun; 110:16-23. PMID: 34098319
Introduction: Pre-eclampsia (PE) is a dangerous placental condition that can lead to premature labour, seizures and death of mother and infant. Several studies have identified altered placental DNA methylation in...
9.
Motwani J, Rodger E, Stockwell P, Baguley B, Macaulay E, Eccles M
Epigenomics . 2021 Mar; 13(8):577-598. PMID: 33781093
The aim of this study was to investigate the role of DNA methylation in invasiveness in melanoma cells. : The authors carried out genome-wide transcriptome (RNA sequencing) and reduced representation...
10.
McDougall L, Powell R, Ratajska M, Lynch-Sutherland C, Hossain S, Wiggins G, et al.
Genes (Basel) . 2021 Mar; 12(2). PMID: 33672422
Melanoma comprises <5% of cutaneous malignancies, yet it causes a significant proportion of skin cancer-related deaths worldwide. While new therapies for melanoma have been developed, not all patients respond well....