Erik L Hewlett
Overview
Explore the profile of Erik L Hewlett including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
34
Citations
944
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Smirnov A, Daily K, Gray M, Ragland S, Werner L, Brittany Johnson M, et al.
J Leukoc Biol
. 2023 Mar;
114(1):1-20.
PMID: 36882066
CR3 (CD11b/CD18; αmβ2 integrin) is a conserved phagocytic receptor. The active conformation of CR3 binds the iC3b fragment of complement C3 as well as many host and microbial ligands, leading...
2.
Gray M, Guerrant R, Hewlett E
Toxins (Basel)
. 2021 Nov;
13(11).
PMID: 34822599
Chinese hamster ovary (CHO) cells respond to pertussis toxin (PT) with a novel clustering pattern, which is dependent on biologically active PT. Since its description in 1983, this cellular response...
3.
Gonyar L, Gelbach P, McDuffie D, Koeppel A, Chen Q, Lee G, et al.
mSphere
. 2019 May;
4(3).
PMID: 31118307
is the causative agent of whooping cough, a serious respiratory illness affecting children and adults, associated with prolonged cough and potential mortality. Whooping cough has reemerged in recent years, emphasizing...
4.
Hoffman C, Gonyar L, Zacca F, Sisti F, Fernandez J, Wong T, et al.
mBio
. 2019 May;
10(3).
PMID: 31088927
encodes and expresses a flagellar apparatus. In contrast, , the causative agent of whooping cough, has historically been described as a nonmotile and nonflagellated organism. The previous statements that was...
5.
Wong T, Hall J, Nowak E, Boehm D, Gonyar L, Hewlett E, et al.
mSphere
. 2019 Apr;
4(2).
PMID: 30996109
causes the disease whooping cough through coordinated control of virulence factors by the virulence gene system. Microarrays and, more recently, RNA sequencing (RNA-seq) have been used to describe gene expression...
6.
Boehm D, Hall J, Wong T, DiVenere A, Sen-Kilic E, Bevere J, et al.
Infect Immun
. 2018 Jul;
86(10).
PMID: 30012638
is the primary causative agent of pertussis (whooping cough), which is a respiratory infection that leads to a violent cough and can be fatal in infants. There is a need...
7.
Gonyar L, Gray M, Christianson G, Mehrad B, Hewlett E
Infect Immun
. 2017 Apr;
85(6).
PMID: 28396321
Pertussis (whooping cough), caused by , is resurging in the United States and worldwide. Adenylate cyclase toxin (ACT) is a critical factor in establishing infection with and acts by specifically...
8.
Wang X, Stapleton J, Klesmith J, Hewlett E, Whitehead T, Maynard J
Biochemistry
. 2017 Feb;
56(9):1324-1336.
PMID: 28177609
Adenylate cyclase toxin (ACT) is an important Bordetella pertussis virulence factor that is not included in current acellular pertussis vaccines. We previously demonstrated that immunization with the repeat-in-toxin (RTX) domain...
9.
Eby J, Gray M, Warfel J, Merkel T, Hewlett E
Clin Vaccine Immunol
. 2016 Nov;
24(1).
PMID: 27760780
Adenylate cyclase toxin (ACT) is an essential virulence factor of Bordetella pertussis, and antibodies to ACT protect against B. pertussis infection in mice. The toxin is therefore a strong candidate...
10.
Eby J, Hoffman C, Gonyar L, Hewlett E
Pathog Dis
. 2015 Oct;
73(9):ftv081.
PMID: 26432818
The nature and timing of the neutrophil response to infection with Bordetella pertussis is influenced by multiple virulence factors expressed by the bacterium. After inoculation of the host airway, the...