Erik Falck-Pedersen
Overview
Explore the profile of Erik Falck-Pedersen including associated specialties, affiliations and a list of published articles.
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Articles
28
Citations
815
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0
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Recent Articles
1.
Yu E, Zahid S, Aloe S, Falck-Pedersen E, Zhou X, Cheung N, et al.
Commun Biol
. 2021 Nov;
4(1):1315.
PMID: 34799676
Telomere maintenance and tumor cell differentiation have been separately implicated in neuroblastoma malignancy. Their mechanistic connection is unclear. We analyzed neuroblastoma cell lines and morphologic subclones representing the adrenergic (ADRN)...
2.
Sarbanes S, Blomen V, Lam E, Heissel S, Luna J, Brummelkamp T, et al.
Proc Natl Acad Sci U S A
. 2021 Jan;
118(1).
PMID: 33443154
The journey from plasma membrane to nuclear pore is a critical step in the lifecycle of DNA viruses, many of which must successfully deposit their genomes into the nucleus for...
3.
Weskamp G, Tushaus J, Li D, Feederle R, Maretzky T, Swendemann S, et al.
J Biol Chem
. 2020 Feb;
295(13):4350-4358.
PMID: 32060096
The metalloprotease ADAM17 (a disintegrin and metalloprotease 17) is a key regulator of tumor necrosis factor α (TNFα), interleukin 6 receptor (IL-6R), and epidermal growth factor receptor (EGFR) signaling. ADAM17...
4.
Janovitz T, Wong S, Young N, Oliveira T, Falck-Pedersen E
Virology
. 2017 Aug;
511:40-48.
PMID: 28806616
The pathogenic autonomous human parvovirus B19 (B19V) productively infects erythroid progenitor cells (EPCs). Functional similarities between B19V nonstructural protein (NS1), a DNA binding endonuclease, and the Rep proteins of Adeno-Associated...
5.
Huffman J, Daniel G, Falck-Pedersen E, Huet A, Smith G, Conway J, et al.
J Virol
. 2017 May;
91(15).
PMID: 28490590
The herpes simplex virus (HSV) capsid is released into the cytoplasm after fusion of viral and host membranes, whereupon dynein-dependent trafficking along microtubules targets it to the nuclear envelope. Binding...
6.
Anghelina D, Lam E, Falck-Pedersen E
J Virol
. 2016 Apr;
90(13):5915-27.
PMID: 27076643
Unlabelled: Infection by adenovirus, a nonenveloped DNA virus, induces antiviral innate and adaptive immune responses. Studies of transformed human and murine cell lines using short hairpin RNA (shRNA) knockdown strategies...
7.
Lam E, Falck-Pedersen E
J Virol
. 2014 Oct;
88(24):14426-39.
PMID: 25297994
Unlabelled: The cGAS/STING DNA sensing complex has recently been established as a predominant pathogen recognition receptor (PRR) for DNA-directed type I interferon (IFN) innate immune activation. Using replication-defective adenovirus vectors...
8.
Janovitz T, Sadelain M, Falck-Pedersen E
Virol J
. 2014 Jan;
11:15.
PMID: 24468291
Background: Adeno-associated virus (AAV) serotype 2 prevalently infects humans and is the only described eukaryotic virus that integrates site-preferentially. In a recent high throughput study, the genome wide distribution of...
9.
Janovitz T, Oliveira T, Sadelain M, Falck-Pedersen E
J Virol
. 2013 Dec;
88(5):2481-8.
PMID: 24335317
Unlabelled: Adeno-associated virus serotype 5 (AAV-5) is a human parvovirus that infects a high percentage of the population. It is the most divergent AAV, the DNA sequence cleaved by the...
10.
Lam E, Stein S, Falck-Pedersen E
J Virol
. 2013 Nov;
88(2):974-81.
PMID: 24198409
Adenovirus (Ad) infection triggers a cell-specific antiviral response following exposure of viral DNA to the intracellular compartment. A variety of DNA sensors (DAI, AIM2, DDx41, RNA polymerase [Pol] III, and...