Erik D Carlson
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Explore the profile of Erik D Carlson including associated specialties, affiliations and a list of published articles.
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9
Citations
489
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Recent Articles
1.
Carlson E, Rajniak J, Sattely E
ACS Synth Biol
. 2023 Aug;
12(8):2329-2338.
PMID: 37558215
Biological DNA transfer into plant cells mediated by represents one of the most powerful tools for the engineering and study of plant systems. Transient expression of transfer DNA (T-DNA) in...
2.
Perez J, Carlson E, Weisser O, Kofman C, Seki K, Des Soye B, et al.
Biotechnol J
. 2021 Dec;
17(4):e2100330.
PMID: 34894206
A genomically recoded Escherichia coli strain that lacks all amber codons and release factor 1 (C321.∆A) enables efficient genetic encoding of chemically diverse non-canonical amino acids (ncAAs) into proteins. While...
3.
Hammerling M, Fritz B, Yoesep D, Kim D, Carlson E, Jewett M
Nat Commun
. 2020 Mar;
11(1):1108.
PMID: 32111839
Directed evolution of the ribosome for expanded substrate incorporation and novel functions is challenging because the requirement of cell viability limits the mutations that can be made. Here we address...
4.
Carlson E, dAquino A, Kim D, Fulk E, Hoang K, Szal T, et al.
Nat Commun
. 2019 Sep;
10(1):3920.
PMID: 31477696
Ribo-T is a ribosome with covalently tethered subunits where core 16S and 23S ribosomal RNAs form a single chimeric molecule. Ribo-T makes possible a functionally orthogonal ribosome-mRNA system in cells....
5.
Yesselman J, Eiler D, Carlson E, Gotrik M, dAquino A, Ooms A, et al.
Nat Nanotechnol
. 2019 Aug;
14(9):866-873.
PMID: 31427748
RNA nanotechnology seeks to create nanoscale machines by repurposing natural RNA modules. The field is slowed by the current need for human intuition during three-dimensional structural design. Here, we demonstrate...
6.
Gan R, Perez J, Carlson E, Ntai I, Isaacs F, Kelleher N, et al.
Biotechnol Bioeng
. 2016 Dec;
114(5):1074-1086.
PMID: 27987323
The ability to site-specifically incorporate non-canonical amino acids (ncAAs) into proteins has made possible the study of protein structure and function in fundamentally new ways, as well as the bio...
7.
Carlson E
ACS Synth Biol
. 2015 Nov;
4(11):1173-5.
PMID: 26585872
Engineering biology is especially challenging given our relatively poor ability to rationally design within life's complex design landscape. Thus, moving through the engineering "design, build, test" cycle multiple times accumulates...
8.
Orelle C, Carlson E, Szal T, Florin T, Jewett M, Mankin A
Nature
. 2015 Jul;
524(7563):119-24.
PMID: 26222032
The ribosome is a ribonucleoprotein machine responsible for protein synthesis. In all kingdoms of life it is composed of two subunits, each built on its own ribosomal RNA (rRNA) scaffold....
9.
Carlson E, Gan R, Hodgman C, Jewett M
Biotechnol Adv
. 2011 Oct;
30(5):1185-94.
PMID: 22008973
Cell-free protein synthesis has emerged as a powerful technology platform to help satisfy the growing demand for simple and efficient protein production. While used for decades as a foundational research...