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Erica M Briggs

Explore the profile of Erica M Briggs including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Michon M, Muller-Schiffmann A, Lingappa A, Yu S, Du L, Deiter F, et al.
Open Biol . 2024 Jun; 14(6):230363. PMID: 38889796
We present a novel small molecule antiviral chemotype that was identified by an unconventional cell-free protein synthesis and assembly-based phenotypic screen for modulation of viral capsid assembly. Activity of PAV-431,...
2.
Michon M, Muller-Schiffmann A, Lingappa A, Yu S, Du L, Deiter F, et al.
bioRxiv . 2021 Dec; PMID: 34931190
We present a novel small molecule antiviral chemotype that was identified by an unconventional cell-free protein synthesis and assembly-based phenotypic screen for modulation of viral capsid assembly. Activity of PAV-431,...
3.
Briggs E, Mita P, Sun X, Ha S, Vasilyev N, Leopold Z, et al.
Mob DNA . 2021 Aug; 12(1):21. PMID: 34425899
Background: The autonomous retroelement Long Interspersed Element-1 (LINE-1) mobilizes though a copy and paste mechanism using an RNA intermediate (retrotransposition). Throughout human evolution, around 500,000 LINE-1 sequences have accumulated in...
4.
Briggs E, McKerrow W, Mita P, Boeke J, Logan S, Fenyo D
Mob DNA . 2021 Feb; 12(1):5. PMID: 33563338
Background: Long INterspersed Element-1 (LINE-1) is an autonomous retroelement able to "copy-and-paste" itself into new loci of the host genome through a process called retrotransposition. The LINE-1 bicistronic mRNA codes...
5.
Briggs E, Spadafora C, Logan S
Mob DNA . 2020 Jan; 10:51. PMID: 31890047
Background: We previously examined expression of Long Interspersed Element-1 (LINE-1) in a variety of prostate cancer cells including hormone-dependent LNCaP cells. These studies demonstrated expression and sub-cellular localization of LINE-1...
6.
Schneider J, Craven T, Kasper A, Yun C, Haugbro M, Briggs E, et al.
Nat Commun . 2018 Oct; 9(1):4396. PMID: 30352998
New chemical inhibitors of protein-protein interactions are needed to propel advances in molecular pharmacology. Peptoids are peptidomimetic oligomers with the capability to inhibit protein-protein interactions by mimicking protein secondary structure...
7.
Briggs E, Ha S, Mita P, Brittingham G, Sciamanna I, Spadafora C, et al.
Mob DNA . 2018 Jan; 9:1. PMID: 29308092
Background: Long Interspersed Nuclear Element-1 (LINE-1) is an autonomous retrotransposon that generates new genomic insertions through the retrotransposition of a RNA intermediate. Expression of LINE-1 is tightly repressed in most...
8.
Mita P, Savas J, Briggs E, Ha S, Gnanakkan V, Yates 3rd J, et al.
J Biol Chem . 2016 Oct; 291(49):25516-25528. PMID: 27780869
URI (unconventional prefoldin RPB5 interactor protein) is an unconventional prefoldin, RNA polymerase II interactor that functions as a transcriptional repressor and is part of a larger nuclear protein complex. The...