Eric Wier
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Explore the profile of Eric Wier including associated specialties, affiliations and a list of published articles.
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115
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Recent Articles
1.
Kirby C, Islam N, Wier E, Alphonse M, Sweren E, Wang G, et al.
J Clin Invest
. 2025 Feb;
PMID: 39903537
Mammalian injury responses are predominantly characterized by fibrosis and scarring rather than functional regeneration. This limited regenerative capacity in mammals could reflect a loss of pro-regeneration programs or active suppression...
2.
Wang G, Sweren E, Andrews W, Li Y, Chen J, Xue Y, et al.
Sci Adv
. 2023 Jan;
9(1):eabo7555.
PMID: 36598999
Tissue injury induces metabolic changes in stem cells, which likely modulate regeneration. Using a model of organ regeneration called wound-induced hair follicle neogenesis (WIHN), we identified skin-resident bacteria as key...
3.
Xue Y, Lyu C, Taylor A, van Ee A, Kiemen A, Choi Y, et al.
Sci Adv
. 2022 Apr;
8(17):eabl8698.
PMID: 35476447
Uniquely among mammalian organs, skin is capable of marked size change in adults, yet the mechanisms underlying this notable capacity are unclear. Here, we use a system of controlled tissue...
4.
Wier E, Asada M, Wang G, Alphonse M, Li A, Hintelmann C, et al.
J Cell Mol Med
. 2021 Oct;
25(21):10008-10019.
PMID: 34623736
Fibrosis is a major health burden across diseases and organs. To remedy this, we study wound-induced hair follicle neogenesis (WIHN) as a model of non-fibrotic healing that recapitulates embryogenesis for...
5.
Wang G, Sweren E, Liu H, Wier E, Alphonse M, Chen R, et al.
Cell Host Microbe
. 2021 Apr;
29(5):777-791.e6.
PMID: 33798492
Environmental factors that enhance regeneration are largely unknown. The immune system and microbiome are attributed roles in repairing and regenerating structure but their precise interplay is unclear. Here, we assessed...
6.
Narkis G, Tzchori I, Cohen T, Holtz A, Wier E, Westphal H
Dev Dyn
. 2012 Mar;
241(4):787-91.
PMID: 22411555
Background: The developing limb has served as an excellent model for studying pattern formation and signal transduction in mammalians. Many of the crucial genes that regulate growth and patterning of...