Eric Tycksen
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Explore the profile of Eric Tycksen including associated specialties, affiliations and a list of published articles.
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44
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1380
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Recent Articles
1.
Brandao W, Jain N, Yin Z, Kleemann K, Carpenter M, Bao X, et al.
Sci Transl Med
. 2025 Jan;
17(781):eadk3690.
PMID: 39813317
Alzheimer's disease (AD) is the most prevalent neurodegenerative disorder. Antiamyloid antibody treatments modestly slow disease progression in mild dementia due to AD. Emerging evidence shows that homeostatic dysregulation of the...
2.
Chermside-Scabbo C, Shuster J, Erdmann-Gilmore P, Tycksen E, Zhang Q, Townsend R, et al.
Aging (Albany NY)
. 2024 Oct;
16(19):12726-12768.
PMID: 39400554
With aging, bone mass declines and the anabolic effects of skeletal loading diminish. While much research has focused on gene transcription, how bone ages and loses its mechanoresponsiveness at the...
3.
Fass S, Mulvey B, Chase R, Yang W, Selmanovic D, Chaturvedi S, et al.
Biol Sex Differ
. 2024 Jun;
15(1):47.
PMID: 38844994
Background: Sex differences in the brain may play an important role in sex-differential prevalence of neuropsychiatric conditions. Methods: In order to understand the transcriptional basis of sex differences, we analyzed...
4.
Litvinchuk A, Suh J, Guo J, Lin K, Davis S, Bien-Ly N, et al.
Neuron
. 2024 Jun;
112(12):2079.
PMID: 38823392
No abstract available.
5.
Giri T, Maloney S, Giri S, Goo Y, Song J, Son M, et al.
iScience
. 2024 Feb;
27(2):108960.
PMID: 38327784
Despite six decades of the use of exogenous oxytocin for management of labor, little is known about its effects on the developing brain. Motivated by controversial reports suggesting a link...
6.
Litvinchuk A, Suh J, Guo J, Lin K, Davis S, Bien-Ly N, et al.
Neuron
. 2023 Nov;
112(3):384-403.e8.
PMID: 37995685
Apolipoprotein E (APOE) is a strong genetic risk factor for late-onset Alzheimer's disease (LOAD). APOE4 increases and APOE2 decreases risk relative to APOE3. In the P301S mouse model of tauopathy,...
7.
Kim Y, Li C, Gu C, Fang Y, Tycksen E, Puri A, et al.
Nat Commun
. 2023 Oct;
14(1):6493.
PMID: 37838725
Misfolded protein aggregates may cause toxic proteinopathy, including autosomal dominant tubulointerstitial kidney disease due to uromodulin mutations (ADTKD-UMOD), a leading hereditary kidney disease. There are no targeted therapies. In our...
8.
Rohatgi N, Zou W, Li Y, Cho K, Collins P, Tycksen E, et al.
Nat Commun
. 2023 Sep;
14(1):5923.
PMID: 37740028
Treatment of osteoporosis commonly diminishes osteoclast number which suppresses bone formation thus compromising fracture prevention. Bone formation is not suppressed, however, when bone degradation is reduced by retarding osteoclast functional...
9.
Fass S, Mulvey B, Yang W, Selmanovic D, Chaturvedi S, Tycksen E, et al.
medRxiv
. 2023 Sep;
PMID: 37693465
Sex differences in the brain may play an important role in sex-differential prevalence of neuropsychiatric conditions. In order to understand the transcriptional basis of sex differences, we analyzed multiple, large-scale,...
10.
Sleep deprivation exacerbates microglial reactivity and Aβ deposition in a -dependent manner in mice
Parhizkar S, Gent G, Chen Y, Rensing N, Gratuze M, Strout G, et al.
Sci Transl Med
. 2023 Apr;
15(693):eade6285.
PMID: 37099634
Sleep loss is associated with cognitive decline in the aging population and is a risk factor for Alzheimer's disease (AD). Considering the crucial role of immunomodulating genes such as that...