Eric Samarut
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Explore the profile of Eric Samarut including associated specialties, affiliations and a list of published articles.
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36
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Recent Articles
11.
Rosch R, Burrows D, Jones L, Peters C, Ruben P, Samarut E
Front Cell Neurosci
. 2020 Jan;
13:556.
PMID: 31920556
The genetic diagnosis of patients with seizure disorders has been improved significantly by the development of affordable next-generation sequencing technologies. Indeed, in the last 20 years, dozens of causative genes...
12.
Rosch R, Samarut E
Curr Biol
. 2019 Dec;
29(23):R1248-R1251.
PMID: 31794761
Investigations of the mechanisms generating epileptic seizures have primarily focused on neurons. However, more systemic research of brain circuits has highlighted an important role of non-neuronal cells such as glia...
13.
Liao M, Kundap U, Rosch R, Burrows D, Meyer M, Bencheikh B, et al.
Dis Model Mech
. 2019 Oct;
12(11).
PMID: 31582559
Epilepsy is a common primary neurological disorder characterized by the chronic tendency of a patient to experience epileptic seizures, which are abnormal body movements or cognitive states that result from...
14.
Gibert Y, Samarut E, Ellis M, Jackman W, Laudet V
Proc Biol Sci
. 2019 Jun;
286(1904):20190401.
PMID: 31185860
The diversity of teeth patterns in actinopterygians is impressive with tooth rows in many locations in the oral and pharyngeal regions. The first-formed tooth has been hypothesized to serve as...
15.
Samarut E, Chalopin D, Riche R, Allard M, Liao M, Drapeau P
PLoS One
. 2019 May;
14(5):e0216159.
PMID: 31048868
Glycine receptors (GlyRs) are ligand-gated chloride channels mediating inhibitory neurotransmission in the brain stem and spinal cord. They function as pentamers composed of alpha and beta subunits for which 5...
16.
Samarut E, Nixon J, Kundap U, Drapeau P, Ellis L
Front Pharmacol
. 2019 Apr;
10:226.
PMID: 30949046
In this study, we aimed to investigate the effect of the two main active cannabinoids extracted from cannabis: Δ-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) on two distinct behavioral models of induced...
17.
Riche R, Liao M, Pena I, Leung K, Lepage N, Greene N, et al.
JCI Insight
. 2018 Nov;
3(21).
PMID: 30385710
Glycine encephalopathy (GE), or nonketotic hyperglycinemia (NKH), is a rare recessive genetic disease caused by defective glycine cleavage and characterized by increased accumulation of glycine in all tissues. Here, based...
18.
Samarut E, Swaminathan A, Riche R, Liao M, Hassan-Abdi R, Renault S, et al.
Epilepsia
. 2018 Oct;
59(11):2061-2074.
PMID: 30324621
Objective: In humans, mutations of the γ-aminobutyric acid receptor subunit 1 (GABRA1) cause either mild or severe generalized epilepsy. Although these epilepsy-causing mutations have been shown to disrupt the receptor...
19.
Swaminathan A, Hassan-Abdi R, Renault S, Siekierska A, Riche R, Liao M, et al.
Curr Biol
. 2018 Jun;
28(12):1924-1937.e5.
PMID: 29861134
Mutations in DEPDC5 are causal factors for a broad spectrum of focal epilepsies, but the underlying pathogenic mechanisms are still largely unknown. To address this question, a zebrafish depdc5 knockout...
20.
Gregoire C, Tobin S, Goldenstein B, Samarut E, Leclerc A, Aumont A, et al.
Front Mol Neurosci
. 2018 May;
11:126.
PMID: 29706867
Environmental enrichment (EE) is a powerful stimulus of brain plasticity and is among the most accessible treatment options for brain disease. In rodents, EE is modeled using multi-factorial environments that...